Accumulation of advanced glycation end products (AGEs) on nucleotides, lipids, and
peptides/proteins are an inevitable component of the aging process in all eukaryotic …

Fructose is associated with the biochemical alterations that promote the development of
metabolic syndrome (MetS), nonalcoholic fatty liver disease, and type 2 diabetes. Its …

The accumulation of advanced glycation end-products (AGEs) in the organic matrix of bone
with aging and chronic disease such as diabetes is thought to increase fracture risk …

Advanced glycation end products (AGEs) are a group of proteins and lipids becoming
glycated and oxidized after persistent contact with reducing sugars or short-chain aldehydes …

Rheumatoid arthritis (RA) is a chronic inflammatory, autoimmune disease that gradually
affects the synovial membrane and joints. Many intrinsic and/or extrinsic factors are crucial in …

抄録 Advanced glycation end-products are toxic by-products of metabolism and are also
acquired from high-temperature processed foods. They promote oxidative damage to …

Background In diabetic metabolic disorders, advanced glycation end products (AGEs)
contribute significantly to the development of cardiovascular diseases (CVD). Aims This …

Individuals with type 2 diabetes (T2D) have a higher fracture risk compared to non-diabetics,
even though their areal bone mineral density is normal to high. Identifying the mechanisms …

Osteocalcin (OC), an abundant non-collagenous protein in bone extracellular matrix, plays a
vital role in both its biological and mechanical function. OC undergoes post-translational …

Glucosepane is a structurally complex protein posttranslational modification that is believed
to exist in all living organisms. Research in humans suggests that glucosepane plays a …