Toll-like receptor 4-related immunostimulatory polysaccharides: Primary structure, activity relationships, and possible interaction models

X Zhang, C Qi, Y Guo, W Zhou, Y Zhang - Carbohydrate polymers, 2016 - Elsevier
Abstract Toll-like receptor (TLR) 4 is an important polysaccharide receptor; however, the
relationships between the structures and biological activities of TLR4 and polysaccharides …

Resource, chemical structure and activity of natural polysaccharides against alcoholic liver damages

Y Yang, J Ji, L Di, J Li, L Hu, H Qiao, L Wang… - Carbohydrate …, 2020 - Elsevier
Many natural polysaccharides from bio-resources hold advantages of multi-functions, high
efficiency, non-toxicity or low side effect, and have strong potentials in protection against …

[HTML][HTML] Mushrooms as potential therapeutic agents in the treatment of cancer: Evaluation of anti-glioma effects of Coprinus comatus, Cantharellus cibarius …

P Nowakowski, R Markiewicz-Żukowska… - Biomedicine & …, 2021 - Elsevier
Cancer incidence rates are on the increase worldwide. The most common brain cancer in
adults is glioblastoma. Currently available treatment modalities are limited and natural …

The two faces of Coprinus comatus—Functional properties and potential hazards

P Nowakowski, SK Naliwajko… - Phytotherapy …, 2020 - Wiley Online Library
Mushrooms have been used for centuries not only as food but also in traditional medicine as
a source of components with pro‐health activity. One of them is Coprinus comatus (OF Müll.) …

[HTML][HTML] Protective mechanism of Coprinus comatus polysaccharide on acute alcoholic liver injury in mice, the metabolomics and gut microbiota investigation

J Yu, J Sun, M Sun, W Li, D Qi, Y Zhang… - Food Science and Human …, 2024 - Elsevier
Coprinus comatus polysaccharide (CCP) has significant hepatoprotective effect. To explore
hepatoprotective mechanism of CCP, the study analyzed preventive effect of CCP on acute …

Antioxidant and hepatoprotective activities of modified polysaccharides from Coprinus comatus in mice with alcohol-induced liver injury

H Zhao, H Li, Q Lai, Q Yang, Y Dong, X Liu… - International journal of …, 2019 - Elsevier
A modified polysaccharide named MPCC from Coprinus comatus (MPCC) was obtained by
the snailase hydrolysis. And the hepatoprotective effects on alcohol-induced liver injury and …

The antioxidant activities of alkalic-extractable polysaccharides from Coprinus comatus on alcohol-induced liver injury in mice

H Zhao, J Zhang, X Liu, Q Yang, Y Dong, L Jia - Scientific Reports, 2018 - nature.com
The aim of this work was to provide a preliminary characterization of alkalic-extractable
polysaccharides (ALPS) from Coprinus comatus, to explore its in vivo antioxidant activities …

Proteoglycan isolated from Corbicula fluminea exerts hepato-protective effects against alcohol-induced liver injury in mice

J Bai, Y Chen, Z Ning, S Liu, C Xu, JK Yan - International journal of …, 2020 - Elsevier
Corbicula fluminea (Asian clam), a freshwater bivalve mollusk, has been consumed in China
for centuries as a health food and traditional Chinese medicine for treating liver diseases …

Coprinus comatus polysaccharides ameliorated carbon tetrachloride-induced liver fibrosis through modulating inflammation and apoptosis

H Zhao, D Li, M Li, L Liu, B Deng, L Jia, F Yang - Food & Function, 2022 - pubs.rsc.org
Liver fibrosis is a serious global public health problem, owing to a lack of effective treatment.
Coprinus comatus polysaccharides (CP), isolated from C. comatus, possess multiple …

First demonstration of protective effects of purified mushroom polysaccharide-peptides against fatty liver injury and the mechanisms involved

S Zhao, S Zhang, W Zhang, Y Gao, C Rong, H Wang… - Scientific Reports, 2019 - nature.com
Fatty liver (FLD) disease is a consequence of metabolic syndrome, which is a health
problem worldwide with a phenomenal rise in prevalence. In this study, two hepatoprotective …