Assessing the psychometric performance of EQ-5D-5L in dementia: a systematic review

AD Keetharuth, H Hussain, D Rowen… - Health and Quality of Life …, 2022 - Springer
Background EQ-5D is widely used for valuing changes in quality of life for economic
evaluation of interventions for people with dementia. There are concerns about EQ-5D-3L in …

Long-term health outcomes of lecanemab in patients with early Alzheimer's disease using simulation modeling

AA Tahami Monfared, A Tafazzoli, W Ye, A Chavan… - Neurology and …, 2022 - Springer
Introduction Alzheimer's disease (AD) is a progressive, neurodegenerative disease and is
the most common cause of dementia. Lecanemab is a humanized monoclonal antibody …

The potential economic value of lecanemab in patients with early Alzheimer's disease using simulation modeling

AA Tahami Monfared, A Tafazzoli, A Chavan… - Neurology and …, 2022 - Springer
Introduction Alzheimer's disease (AD) is a progressive, neurodegenerative disease that
affects memory, thinking, and behavior and places a substantial economic burden on …

A path to improved Alzheimer's care: simulating long-term health outcomes of lecanemab in early Alzheimer's disease from the CLARITY AD trial

AA Tahami Monfared, W Ye, A Sardesai, H Folse… - Neurology and …, 2023 - Springer
Introduction Alzheimer's disease (AD), a progressive neurodegenerative disease, is the
main cause of dementia and one of the leading causes of death for elderly people in the …

Convergent validity of EQ-5D with core outcomes in dementia: a systematic review

H Hussain, A Keetharuth, D Rowen… - Health and Quality of Life …, 2022 - Springer
Objectives To explore through a systematic review, the convergent validity of EQ-5D (EQ-5D-
3L and EQ-5D-5L (total score and dimensions)) with core outcomes in dementia and …

Health-related quality of life in subjective cognitive decline and mild cognitive impairment: a longitudinal cohort analysis

S Aye, V Bouteloup, A Tate, A Wimo, R Handels… - Alzheimer's Research & …, 2023 - Springer
Background Health-related quality of life (HR-QoL) is an important outcome for patients and
crucial for demonstrating the value of new treatments. Health utility estimates in subjective …

Synergistic Impact of Visual and Cognitive Impairments on Health-Related Quality of Life in a Multiethnic Asian Population

TA Vu, P Gupta, ATL Gan, EK Fenwick, REK Man… - Gerontology, 2024 - karger.com
Introduction: The concomitant impact of visual impairment (VI) and cognitive impairment (CI)
on health-related quality of life (HRQoL) in older adults is unclear. We aimed to determine …

Predicted lifetime health outcomes for aducanumab in patients with early Alzheimer's disease

WL Herring, IG Gould, H Fillit, P Lindgren… - Neurology and …, 2021 - Springer
Introduction Alzheimer's disease (AD) is a chronic and progressive neurodegenerative
disease that places a substantial burden on patients and caregivers. Aducanumab is the first …

Understanding the lived experiences of family caregivers of individuals with dementia in Soweto, a South African Township

A Mahomed, C Pretorius - Dementia, 2022 - journals.sagepub.com
This study was undertaken to understand South African family caregivers' lived experiences
of individuals living with dementia in a predominantly Black African township. A …

Machine learning analyses identify multi-modal frailty factors that selectively discriminate four cohorts in the Alzheimer's disease spectrum: a COMPASS-ND study

L Bohn, SM Drouin, GP McFall, DB Rolfson… - BMC geriatrics, 2023 - Springer
Background Frailty indicators can operate in dynamic amalgamations of disease conditions,
clinical symptoms, biomarkers, medical signals, cognitive characteristics, and even health …