Bacteria come in a range of shapes, including round, rod-shaped, curved and spiral cells.
This morphological diversity implies that different mechanisms exist to guide proper cell …

In dividing cells, chromosome duplication once per generation must be coordinated with
faithful segregation of newly replicated chromosomes and with cell growth and division …

Initiation of chromosome segregation in bacteria is achieved by proteins acting near the
origin of replication. Here, we report that the precise choreography of the terminus region of …

Bacteria use the replication origin-to-terminus polarity of their circular chromosomes to
control DNA transactions during the cell cycle. Segregation starts by active migration of the …

We examine whether the E scherichia coli chromosome is folded into a self‐adherent
nucleoprotein complex, or alternately is a confined but otherwise unconstrained self …

Plasmids are self-replicating pieces of DNA typically bearing non-essential genes. Given
that plasmids represent a metabolic burden to the host, mechanisms ensuring plasmid …

In bacteria, chromosomal architecture shows strong spatial and temporal organization, and
regulates key cellular functions, such as transcription. Tracking the motion of chromosomal …

Highlights•The nucleoid is self-adherent and helical ellipsoidal via radial plectoneme
loops.•The nucleoid is viscoelastic with ATP-mediated enhancement of thermal …

The study of chromosomal organization and segregation in a handful of bacteria has
revealed surprising variety in the mechanisms mediating such fundamental processes. In …

The chromosome of archetypal bacteria E. coli is known for a complex topology with a 4.6×
106 base pairs (bp) long sequence of nucleotides packed within a micrometer-sized cellular …