Distinctions and similarities of cell bioenergetics and the role of mitochondria in hypoxia, cancer, and embryonic development

P Ježek, L Plecitá-Hlavatá, K Smolková… - The International Journal …, 2010 - Elsevier
In this review we compare situations under which the major cellular role of mitochondria,
oxidative phosphorylation (OXPHOS), is transiently suppressed. Two types of cellular …

Mitochondrial nitric oxide synthase, mitochondrial brain dysfunction in aging, and mitochondria-targeted antioxidants

A Navarro, A Boveris - Advanced drug delivery reviews, 2008 - Elsevier
This paper reviews the current ideas on nitric oxide (NO) physiology in brain and other
mammalian organs and on the subcellular distribution of nitric oxide synthases (NOS) …

Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells

MS Parihar, A Parihar, M Fujita, M Hashimoto… - The international journal …, 2009 - Elsevier
Overexpression of alpha-synuclein and oxidative stress has been implicated in the neuronal
cell death in Parkinson's disease. Alpha-synuclein associates with mitochondria and …

Mitochondria-mediated cardioprotection by trimetazidine in rabbit heart failure

EN Dedkova, LK Seidlmayer, LA Blatter - Journal of molecular and cellular …, 2013 - Elsevier
Trimetazidine (TMZ) is used successfully for treatment of ischemic cardiomyopathy, however
its therapeutic potential in heart failure (HF) remains to be established. While the …

Characteristics and function of cardiac mitochondrial nitric oxide synthase

EN Dedkova, LA Blatter - The Journal of physiology, 2009 - Wiley Online Library
We used laser scanning confocal microscopy in combination with the nitric oxide (NO)‐
sensitive fluorescent dye DAF‐2 and the reactive oxygen species (ROS)‐sensitive dyes CM …

Endotoxemia impairs heart mitochondrial function by decreasing electron transfer, ATP synthesis and ATP content without affecting membrane potential

V Vanasco, ND Magnani, MC Cimolai… - Journal of bioenergetics …, 2012 - Springer
Abstract Acute endotoxemia (LPS, 10 mg/kg ip, Sprague Dawley rats, 45 days old, 180 g)
decreased the O 2 consumption of rat heart (1 mm 3 tissue cubes) by 33%(from 4.69 to 3.11 …

[HTML][HTML] Синтаза оксида азота и эндогенный оксид азота в физиологии и патологии клетки

ЕВ Пожилова, ВЕ Новиков - Вестник Смоленской …, 2015 - cyberleninka.ru
В обзорной статье представлен анализ результатов научных исследований о роли
синтазы оксида азота (NOS) и эндогенного оксида азота (NO) в функционировании …

[HTML][HTML] Mitochondrial mechanisms by which gasotransmitters (H2S, NO and CO) protect cardiovascular system against hypoxia

I Shemarova, V Nesterov, L Emelyanova… - Frontiers in Bioscience …, 2021 - imrpress.com
Over past few years, there has been a dramatic increase in studying physiological
mechanisms of the activity of various signaling low-molecular molecules that directly or …

Fluorescence-based nitric oxide sensing by Cu (II) complexes that can be trapped in living cells

LE McQuade, SJ Lippard - Inorganic chemistry, 2010 - ACS Publications
A series of symmetrical, fluorescein-derived ligands appended with two derivatized 2-methyl-
8-aminoquinolines were prepared and spectroscopically characterized. The ligands FL2 …

Sustained deficiency of mitochondrial complex I activity during long periods of survival after seizures induced in immature rats by homocysteic acid

J Folbergrová, P Ješina, R Haugvicová, V Lisý… - Neurochemistry …, 2010 - Elsevier
Our previous work demonstrated the marked decrease of mitochondrial complex I activity in
the cerebral cortex of immature rats during the acute phase of seizures induced by bilateral …