Lipid droplets (LDs) are complex and metabolically active organelles. They are composed of
a neutral lipid core surrounded by a monolayer of phospholipids and proteins. LD …

Liver fibrosis is an abnormal wound repair response caused by a variety of chronic liver
injuries, which is characterized by over-deposition of diffuse extracellular matrix (ECM) and …

Obesity is associated with many adverse health effects, such as an increased
cardiometabolic risk. Despite higher adiposity for a given BMI, premenopausal women are at …

摘要非酒精性脂肪性肝病(Non‐alcoholic fatty liver disease, NAFLD) 是西方国家最常见的肝脏
疾病, 在普通人群中的患病率约为20%–33%. 我国已报道的研究数据显示 …

Several animal studies have emphasized the role of gut microbiota in nonalcoholic fatty liver
disease (NAFLD). However, data about gut dysbiosis in human NAFLD remain scarce in the …

Liver fibrosis is a reversible wound-healing process aimed at maintaining organ integrity,
and presents as the critical pre-stage of liver cirrhosis, which will eventually progress to …

Understanding the molecular mechanisms underlying liver fibrogenesis is fundamentally
relevant to developing new treatments that are independent of the underlying etiology. The …

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver dysfunction in
the Western world and is increasing owing to its close association with obesity and insulin …

NAFLD is a spectrum of progressive liver disease that encompasses simple steatosis,
NASH, fibrosis and, ultimately, cirrhosis. NAFLD is recognized as the hepatic component of …

Nonalcoholic fatty liver disease (NAFLD) is a frequent cause of chronic liver diseases,
ranging from simple steatosis to nonalcoholic steatohepatitis (NASH)-related liver cirrhosis …