Fluid mechanics of heart valves and their replacements

F Sotiropoulos, TB Le, A Gilmanov - Annual Review of Fluid …, 2016 - annualreviews.org
As the pulsatile cardiac blood flow drives the heart valve leaflets to open and close, the flow
in the vicinity of the valve resembles a pulsed jet through a nonaxisymmetric orifice with a …

The clinical assessment of intraventricular flows

J Bermejo, P Martínez-Legazpi… - Annual Review of Fluid …, 2015 - annualreviews.org
Recent advances in imaging techniques have allowed physicians to obtain robust
measurements of intracardiac flows in the clinical setting. Consequently, the physiological …

Contribution of the diastolic vortex ring to left ventricular filling

P Martínez-Legazpi, J Bermejo, Y Benito, R Yotti… - Journal of the American …, 2014 - jacc.org
Background: Intraventricular fluid dynamics can be assessed clinically using imaging. The
contribution of vortex structures to left ventricular (LV) diastolic function has never been …

Assessment of viscous energy loss and the association with three‐dimensional vortex ring formation in left ventricular inflow: In vivo evaluation using four‐dimensional …

MSM Elbaz, RJ van der Geest… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose To evaluate viscous energy loss and the association with three‐dimensional (3D)
vortex ring formation in left ventricular (LV) blood flow during diastolic filling. Theory and …

[HTML][HTML] Effect of the mitral valve on diastolic flow patterns

JH Seo, V Vedula, T Abraham, AC Lardo, F Dawoud… - Physics of …, 2014 - pubs.aip.org
The leaflets of the mitral valve interact with the mitral jet and significantly impact diastolic
flow patterns, but the effect of mitral valve morphology and kinematics on diastolic flow and …

Vortex ring behavior provides the epigenetic blueprint for the human heart

PM Arvidsson, SJ Kovács, J Töger, R Borgquist… - Scientific reports, 2016 - nature.com
The laws of fluid dynamics govern vortex ring formation and precede cardiac development
by billions of years, suggesting that diastolic vortex ring formation is instrumental in defining …

Vortices formed on the mitral valve tips aid normal left ventricular filling

JJ Charonko, R Kumar, K Stewart, WC Little… - Annals of biomedical …, 2013 - Springer
For the left ventricle (LV) to function as an effective pump it must be able to fill from a low left
atrial pressure. However, this ability is lost in patients with heart failure. We investigated LV …

Intraventricular vortex properties in nonischemic dilated cardiomyopathy

J Bermejo, Y Benito, M Alhama… - American Journal …, 2014 - journals.physiology.org
Vortices may have a role in optimizing the mechanical efficiency and blood mixing of the left
ventricle (LV). We aimed to characterize the size, position, circulation, and kinetic energy …

Comparative numerical study on left ventricular fluid dynamics after dilated cardiomyopathy

JO Mangual, E Kraigher-Krainer, A De Luca… - Journal of …, 2013 - Elsevier
INTRODUCTION: The role of flow on the progression of left ventricular (LV) remodeling has
been presumed, although measurements are still limited and the intraventricular flow pattern …

4D-flow cardiac magnetic resonance-derived vorticity is sensitive marker of left ventricular diastolic dysfunction in patients with mild-to-moderate chronic obstructive …

M Schäfer, S Humphries, KR Stenmark… - European Heart …, 2018 - academic.oup.com
Aims To investigate the possibility that vorticity assessed by four-dimensional flow cardiac
magnetic resonance (4D-Flow CMR) in the left ventricle of patients with mild-to-moderate …