Cancer neuroscience: State of the field, emerging directions

F Winkler, HS Venkatesh, M Amit, T Batchelor, IE Demir… - Cell, 2023 - cell.com
The nervous system governs both ontogeny and oncology. Regulating organogenesis
during development, maintaining homeostasis, and promoting plasticity throughout life, the …

The updated landscape of tumor microenvironment and drug repurposing

MZ Jin, WL Jin - Signal transduction and targeted therapy, 2020 - nature.com
Accumulating evidence shows that cellular and acellular components in tumor
microenvironment (TME) can reprogram tumor initiation, growth, invasion, metastasis, and …

The neuroscience of cancer

R Mancusi, M Monje - Nature, 2023 - nature.com
The nervous system regulates tissue stem and precursor populations throughout life.
Parallel to roles in development, the nervous system is emerging as a critical regulator of …

Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome

R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

Stress and cancer: mechanisms, significance and future directions

A Eckerling, I Ricon-Becker, L Sorski… - Nature Reviews …, 2021 - nature.com
The notion that stress and cancer are interlinked has dominated lay discourse for decades.
More recent animal studies indicate that stress can substantially facilitate cancer …

Neuroimmune interactions: from the brain to the immune system and vice versa

R Dantzer - Physiological reviews, 2018 - journals.physiology.org
Because of the compartmentalization of disciplines that shaped the academic landscape of
biology and biomedical sciences in the past, physiological systems have long been studied …

Nerves in cancer

AH Zahalka, PS Frenette - Nature Reviews Cancer, 2020 - nature.com
The contribution of nerves to the pathogenesis of malignancies has emerged as an
important component of the tumour microenvironment. Recent studies have shown that …

Fluids and their mechanics in tumour transit: shaping metastasis

G Follain, D Herrmann, S Harlepp, V Hyenne… - Nature Reviews …, 2020 - nature.com
Metastasis is a dynamic succession of events involving the dissemination of tumour cells to
distant sites within the body, ultimately reducing the survival of patients with cancer. To …

Perioperative events influence cancer recurrence risk after surgery

JG Hiller, NJ Perry, G Poulogiannis, B Riedel… - Nature reviews Clinical …, 2018 - nature.com
Surgery is a mainstay treatment for patients with solid tumours. However, despite surgical
resection with a curative intent and numerous advances in the effectiveness of (neo) …

Cancer metastasis: molecular mechanisms and clinical perspectives

SU Khan, K Fatima, F Malik, H Kalkavan… - Pharmacology & …, 2023 - Elsevier
Metastatic progression combined with non-responsiveness towards systemic therapy often
shapes the course of disease for cancer patients and commonly determines its lethal …