[HTML][HTML] The lymphatic vasculature in the 21st century: novel functional roles in homeostasis and disease

G Oliver, J Kipnis, GJ Randolph, NL Harvey - Cell, 2020 - cell.com
Mammals have two specialized vascular circulatory systems: the blood vasculature and the
lymphatic vasculature. The lymphatic vasculature is a unidirectional conduit that returns …

Notch signaling in development, tissue homeostasis, and disease

C Siebel, U Lendahl - Physiological reviews, 2017 - journals.physiology.org
Notch signaling is an evolutionarily highly conserved signaling mechanism, but in contrast to
signaling pathways such as Wnt, Sonic Hedgehog, and BMP/TGF-β, Notch signaling occurs …

Lymphatic vessels in bone support regeneration after injury

L Biswas, J Chen, J De Angelis, A Singh… - Cell, 2023 - cell.com
Blood and lymphatic vessels form a versatile transport network and provide inductive signals
to regulate tissue-specific functions. Blood vessels in bone regulate osteogenesis and …

Vascular endothelial cells: heterogeneity and targeting approaches

JK Hennigs, C Matuszcak, M Trepel, J Körbelin - Cells, 2021 - mdpi.com
Forming the inner layer of the vascular system, endothelial cells (ECs) facilitate a multitude
of crucial physiological processes throughout the body. Vascular ECs enable the vessel wall …

Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI

M Absinta, SK Ha, G Nair, P Sati, NJ Luciano… - elife, 2017 - elifesciences.org
Here, we report the existence of meningeal lymphatic vessels in human and nonhuman
primates (common marmoset monkeys) and the feasibility of noninvasively imaging and …

Lymphatic vessels in cancer

LC Dieterich, C Tacconi, L Ducoli… - Physiological …, 2022 - journals.physiology.org
The lymphatic system, composed of initial and collecting lymphatic vessels as well as lymph
nodes that are present in almost every tissue of the human body, acts as an essential …

[HTML][HTML] Lymphatic vessel network structure and physiology

JW Breslin, Y Yang, JP Scallan, RS Sweat… - Comprehensive …, 2018 - ncbi.nlm.nih.gov
The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue,
which has the holistic function to maintain the local physiologic environment for every cell in …

Lymphoangiocrine signals promote cardiac growth and repair

X Liu, E De la Cruz, X Gu, L Balint, M Oxendine-Burns… - Nature, 2020 - nature.com
Recent studies have suggested that lymphatics help to restore heart function after cardiac
injury,,,,–. Here we report that lymphatics promote cardiac growth, repair and …

[HTML][HTML] Intestinal enteroendocrine lineage cells possess homeostatic and injury-inducible stem cell activity

KS Yan, O Gevaert, GXY Zheng, B Anchang… - Cell stem cell, 2017 - cell.com
Several cell populations have been reported to possess intestinal stem cell (ISC) activity
during homeostasis and injury-induced regeneration. Here, we explored inter-relationships …

FGF-dependent metabolic control of vascular development

P Yu, K Wilhelm, A Dubrac, JK Tung, TC Alves… - Nature, 2017 - nature.com
Blood and lymphatic vasculatures are intimately involved in tissue oxygenation and fluid
homeostasis maintenance. Assembly of these vascular networks involves sprouting …