Owing to a sessile lifestyle in nature, plants are routinely faced with diverse hostile
environments such as various abiotic and biotic stresses, which lead to accumulation of free …

As an important carbon fixation carrier, the plant is extremely susceptible to a variety of
environmental influences during its growth and development, which not only manifest …

Hepatocellular carcinoma (HCC) is a lethal and aggressive human malignancy. The present
study examins the anti‐tumor effects of deubiquitylating enzymes (DUB) inhibitors in HCC. It …

Seed size and weight are key traits determining crop yield, which often undergo strongly
artificial selection during crop domestication. Although seed sizes differ significantly …

Anaplastic thyroid cancer (ATC) is one of the most lethal and aggressive human
malignancies, with no effective treatment currently available. The Hippo tumor suppressor …

Background Bladder cancer is one of the most commonly diagnosed urological malignant
tumor. The Hippo tumor suppressor pathway is highly conserved in mammals and plays an …

Breast cancer is the most commonly diagnosed malignant tumor among females. Estrogen
receptor α (ERα) is initially expressed in 70% of breast cancers and is a well-known target of …

Abstract AtUBC32, AtUBC33, and AtUBC34 comprise Arabidopsis group XIV E2 ubiquitin-
conjugating enzymes. Yeast two-hybrid, in vitro pull-down, and bimolecular fluorescence …

Abstract Multisubunit SKP1/Cullin1/F-box (SCF) E3 ligases play essential roles in regulating
the stability of crucial regulatory factors and controlling growth and development in …

Ubiquitin and similar proteins, such as SUMO, are utilized by plants to modify target proteins
to rapidly change their stability and activity in cells. This review will provide an overview of …