Heart failure (HF) is frequently the consequence of sustained, abnormal neurohormonal,
and mechanical stress and remains a leading cause of death worldwide. The key …

A diabetic foot ulcer (DFU) is one of the major complications of diabetes. Wound healing
under diabetic conditions is often impaired. This is in part due to the excessive oxidative …

Impaired wound healing is a debilitating complication of diabetes that leads to significant
morbidity, particularly foot ulcers. Natural products have shown to be effective in treating skin …

Obesity-mediated metabolic syndrome remains the leading cause of death worldwide.
Among many potential targets for pharmacological intervention, a promising strategy …

Drug repurposing has gained significant interest in recent years due to the high costs
associated with de novo drug development; however, comprehensive pharmacological …

Background Cellular senescence is a stable cell-cycle arrest induced by telomere
shortening and various types of cellular stress including oxidative stress, oncogene …

Background: Cardiovascular disease (CVD) remains the leading cause of disease burden
worldwide. Ferroptosis, an iron-dependent form of programmed cell death, is characterized …

Gastrointestinal (GI) tract cancers pose a significant pharmacological challenge for
researchers in terms of the discovery of molecular agents and the development of targeted …

The development of cardiac dysfunction caused by microbial infection predicts high mortality
in sepsis patients. Specialized pro-resolving mediators (SPMs) mediate resolution of …

Sepsis is one of the most prevalent diseases in the world. The development of cardiac
dysfunction in sepsis results in an increase of mortality. It is known that Bruton's tyrosine …