Tau aggregation into insoluble filaments is the defining pathological hallmark of tauopathies. However, it is not known what controls the formation and templated seeding of strain-specific …
The rational molecular design of non-fullerene acceptors (NFAs) in organic solar cells (OSCs) can profoundly influence the photovoltaic (OPV) performance. To date, NFA …
Cholesterol has been conjectured to be a modulator of the amyloid cascade, the mechanism that produces the amyloid-β (Aβ) peptides implicated in the onset of Alzheimer's disease …
Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the structure, function, and motion of proteins for students, faculty, and researchers at all levels …
The flexible regions represented by loops have been the focus of protein stability engineering. However, residues located in specific rigid regions are also crucial for protein …
Polyglutamine (polyQ) tracts are regions of low sequence complexity frequently found in transcription factors. Tract length often correlates with transcriptional activity and expansion …
L Xu, Z Wang, J Chen, S Chen, W Yang, Y Ren… - Nature …, 2022 - nature.com
The fundamental relationships between the structure and properties of liquids are far from being well understood. For instance, the structural origins of many liquid anomalies still …
I Łukaszewska, S Lalik, A Bukowczan, M Marzec… - Journal of Molecular …, 2023 - Elsevier
A series of linear non-isocyanate polyhydroxyurethanes (NIPUs) were synthesized by aminolysis of a PPO bis-cyclic carbonate with two diamines, one of which …
The ability to stabilize enzymes and other proteins has wide-ranging applications. Most protocols for enhancing enzyme stability require multiple rounds of high-throughput …