Infrared difference spectroscopy of proteins: from bands to bonds

VA Lorenz-Fonfria - Chemical reviews, 2020 - ACS Publications
Infrared difference spectroscopy probes vibrational changes of proteins upon their
perturbation. Compared with other spectroscopic methods, it stands out by its sensitivity to …

Posttranslational modifications mediate the structural diversity of tauopathy strains

T Arakhamia, CE Lee, Y Carlomagno, M Kumar… - Cell, 2020 - cell.com
Tau aggregation into insoluble filaments is the defining pathological hallmark of tauopathies.
However, it is not known what controls the formation and templated seeding of strain-specific …

Non-fullerene acceptors with direct and indirect hexa-fluorination afford> 17% efficiency in polymer solar cells

G Li, LW Feng, S Mukherjee, LO Jones… - Energy & …, 2022 - pubs.rsc.org
The rational molecular design of non-fullerene acceptors (NFAs) in organic solar cells
(OSCs) can profoundly influence the photovoltaic (OPV) performance. To date, NFA …

Cholesterol and Lipid Rafts in the Biogenesis of Amyloid-β Protein and Alzheimer's Disease

GA Pantelopulos, CB Abraham… - Annual Review of …, 2024 - annualreviews.org
Cholesterol has been conjectured to be a modulator of the amyloid cascade, the mechanism
that produces the amyloid-β (Aβ) peptides implicated in the onset of Alzheimer's disease …

[图书][B] Introduction to proteins: structure, function, and motion

A Kessel, N Ben-Tal - 2018 - taylorfrancis.com
Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the
structure, function, and motion of proteins for students, faculty, and researchers at all levels …

Enhanced Thermostability of Candida Ketoreductase by Computation-Based Cross-Regional Combinatorial Mutagenesis

C Chen, BH Guan, Q Geng, YC Zheng, Q Chen… - ACS …, 2023 - ACS Publications
The flexible regions represented by loops have been the focus of protein stability
engineering. However, residues located in specific rigid regions are also crucial for protein …

Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in a transcription factor

A Escobedo, B Topal, MBA Kunze, J Aranda… - Nature …, 2019 - nature.com
Polyglutamine (polyQ) tracts are regions of low sequence complexity frequently found in
transcription factors. Tract length often correlates with transcriptional activity and expansion …

Folded network and structural transition in molten tin

L Xu, Z Wang, J Chen, S Chen, W Yang, Y Ren… - Nature …, 2022 - nature.com
The fundamental relationships between the structure and properties of liquids are far from
being well understood. For instance, the structural origins of many liquid anomalies still …

[HTML][HTML] Tailoring the physical properties of non-isocyanate polyurethanes by introducing secondary amino groups along their main chain

I Łukaszewska, S Lalik, A Bukowczan, M Marzec… - Journal of Molecular …, 2023 - Elsevier
A series of linear non-isocyanate polyhydroxyurethanes (NIPUs) were synthesized by
aminolysis of a PPO bis-cyclic carbonate with two diamines, one of which …

A computational library design protocol for rapid improvement of protein stability: FRESCO

HJ Wijma, MJLJ Fürst, DB Janssen - Protein engineering: Methods and …, 2018 - Springer
The ability to stabilize enzymes and other proteins has wide-ranging applications. Most
protocols for enhancing enzyme stability require multiple rounds of high-throughput …