Mycobacterium abscessus infection leads to enhanced production of type 1 interferon and NLRP3 inflammasome activation in murine macrophages via mitochondrial …

BR Kim, BJ Kim, YH Kook, BJ Kim - PLoS pathogens, 2020 - journals.plos.org
Mycobacterium abscessus (MAB) is a rapidly growing mycobacterium (RGM), and infections
with this pathogen have been increasing worldwide. Recently, we reported that rough type …

Recombinant BCG vaccines: molecular features and their influence in the expression of foreign genes

TL Oliveira, C Rizzi, OA Dellagostin - Applied Microbiology and …, 2017 - Springer
Recombinant Mycobacterium bovis BCG vaccines (rBCG) were first developed in the 1990s
as a means of expressing antigens from multiple pathogens. This review examines the key …

Advances and challenges in recombinant Mycobacterium bovis BCG-based HIV vaccine development: lessons learned

A Kilpeläinen, M Maya-Hoyos, N Saubí… - Expert Review of …, 2018 - Taylor & Francis
ABSTRACT Introduction: Human Immunodeficiency Virus/Acquired Immune Deficiency
Syndrome, tuberculosis, and malaria are responsible for most human deaths produced by …

Phagosome Escape of Rough Mycobacterium abscessus Strains in Murine Macrophage via Phagosomal Rupture Can Lead to Type I Interferon Production and Their …

BR Kim, BJ Kim, YH Kook, BJ Kim - Frontiers in Immunology, 2019 - frontiersin.org
Mycobacterium abscessus complex (MAB) is a rapidly growing mycobacterium (RGM)
whose clinical significance as an emerging human pathogen has been increasing …

Recombinant Mycobacterium paragordonae Expressing SARS-CoV-2 Receptor-Binding Domain as a Vaccine Candidate Against SARS-CoV-2 Infections

BJ Kim, H Jeong, H Seo, MH Lee, HM Shin… - Frontiers in …, 2021 - frontiersin.org
At present, concerns that the recent global emergence of SARS-CoV-2 variants could
compromise the current vaccines have been raised, highlighting the urgent demand for new …

[HTML][HTML] Recombinant Mycobacterium smegmatis delivering a fusion protein of human macrophage migration inhibitory factor (MIF) and IL-7 exerts an anticancer effect …

H Jeong, SY Lee, H Seo, BJ Kim - Journal for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Macrophage migration inhibitory factor (MIF) is a pleotropic inflammatory
cytokine that is overexpressed in a number of cancer types including most types of human …

Comprehensive in silico survey of the Mycolicibacterium mobilome reveals an as yet underexplored diversity

SM Morgado, ACP Vicente - Microbial genomics, 2021 - microbiologyresearch.org
The mobilome plays a crucial role in bacterial adaptation and is therefore a starting point to
understand and establish the gene flow occurring in the process of bacterial evolution. This …

Quantifying bacterial cell lysis using GFP based fluorimetric assay

M Sharma, JL Tyagi, KM Poluri - International journal of biological …, 2019 - Elsevier
Quantitative measurement of cell lysis against a given microbial strain is essential to
calculate the antimicrobial potency of protein/peptide/nanomaterial based formulations …

A secreted form of chorismate mutase (Rv1885c) in Mycobacterium bovis BCG contributes to pathogenesis by inhibiting mitochondria-mediated apoptotic cell death …

MH Lee, HL Kim, H Seo, S Jung, BJ Kim - Journal of Biomedical Science, 2023 - Springer
Background Mycobacterium tuberculosis is the causative agent of tuberculosis (TB), and its
pathogenicity is associated with its ability to evade the host defense system. The secretory …

Development of a live recombinant BCG expressing human immunodeficiency virus type 1 (HIV-1) gag using a pMyong2 vector system: Potential use as a novel HIV-1 …

BJ Kim, BR Kim, YH Kook, BJ Kim - Frontiers in immunology, 2018 - frontiersin.org
Even though the rate of new human immunodeficiency virus type 1 (HIV-1) infections is
gradually decreasing worldwide, an effective preventive vaccine for HIV-1 is still urgently …