L-arginine and nitric oxide in CNS function and neurodegenerative diseases

M Virarkar, L Alappat, PG Bradford… - Critical reviews in food …, 2013 - Taylor & Francis
One of the main functions of L-arginine (ARG) is the synthesis of nitric oxide (NO). NO is an
important regulator of physiological processes in the central nervous system (CNS). NO …

S-denitrosylation: a crosstalk between glutathione and redoxin systems

S Chakraborty, E Sircar, C Bhattacharyya, A Choudhuri… - Antioxidants, 2022 - mdpi.com
S-nitrosylation of proteins occurs as a consequence of the derivatization of cysteine thiols
with nitric oxide (NO) and is often associated with diseases and protein malfunction …

Alzheimer's disease: A contextual link with nitric oxide synthase

H Dubey, K Gulati, A Ray - Current Molecular Medicine, 2020 - ingentaconnect.com
Nitric oxide (NO) is a gasotransmitter with pleiotropic effects which has made a great impact
on biology and medicine. A multidimensional neuromodulatory role of NO has been shown …

Enhancing S-nitrosoglutathione reductase decreases S-nitrosylation of Drp1 and reduces neuronal apoptosis in experimental subarachnoid hemorrhage both in vivo …

L Wang, Z Wang, W You, Z Yu, X Li, H Shen, H Li… - Brain Research …, 2022 - Elsevier
Subarachnoid hemorrhage (SAH) is a hemorrhagic stroke with a high mortality and disability
rate. Nitric oxide (NO) can promote blood supply through vasodilation, leading to protein S …

Nitric oxide and anxiety

K Gulati, N Rai, A Ray - Vitamins and hormones, 2017 - Elsevier
Anxiety is a common neuropsychiatric disorder which affects both physical and mental
health. Complex neurobiological mechanisms are involved in the genesis of anxiety, and the …

Antidepressant-like effects of N-acetyl-L-cysteine in rats

FR Ferreira, C Biojone, SRL Joca… - Behavioural …, 2008 - journals.lww.com
Oxidative stress disturbances have been reported in depressed patients and in animals
submitted to stress. Recent evidence suggests that antidepressants may have antioxidant …

Intracellular glutathione mediates the denitrosylation of protein nitrosothiols in the rat spinal cord

JM Romero, OA Bizzozero - Journal of neuroscience research, 2009 - Wiley Online Library
Protein S‐nitrosothiols (PrSNOs) have been implicated in the pathophysiology of
neuroinflammatory and neurodegenerative disorders. Although the metabolically instability …

S-Nitrosylation of the epidermal growth factor receptor: a regulatory mechanism of receptor tyrosine kinase activity

M Murillo-Carretero, A Torroglosa, C Castro… - Free Radical Biology …, 2009 - Elsevier
Nitric oxide (NO) donors inhibit the epidermal growth factor (EGF)-dependent auto (trans)
phosphorylation of the EGF receptor (EGFR) in several cell types in which NO exerts …

Nitrosative stress inhibits aminoacylation and editing activities of mitochondrial threonyl-tRNA synthetase by S-nitrosation

WQ Zheng, Y Zhang, Q Yao, Y Chen… - Nucleic Acids …, 2020 - academic.oup.com
Abstract Structure and/or function of proteins are frequently affected by oxidative/nitrosative
stress via posttranslational modifications. Aminoacyl-tRNA synthetases (aaRSs) constitute a …

[PDF][PDF] S-nitrosylation/denitrosylation and apoptosis of immune cells

S Duan, C Chen - Cell Mol Immunol, 2007 - cmi.ustc.edu.cn
Nitric oxide (NO) as an immunoregulatory molecule, predominantly depending on S-
nitrosylation, acts as a versatile player that executes its regulation and signal transduction …