High-throughput virtual screening of Streptomyces spp. metabolites as antiviral inhibitors against the Nipah virus matrix protein

MAB Macalalad, NMO Odchimar, FL Orosco - Computational Biology and …, 2024 - Elsevier
Nipah virus (NiV) remains a significant global concern due to its impact on both the
agricultural industry and human health, resulting in substantial economic and health …

Advancing one health vaccination: In silico design and evaluation of a multi-epitope subunit vaccine against Nipah virus for cross-species immunization using …

EC Banico, EMJS Sira, LE Fajardo, ANG Dulay… - PloS one, 2024 - journals.plos.org
The resurgence of the Nipah virus (NiV) in 2023 has raised concerns for another potentially
severe pandemic, given its history of high mortality from previous outbreaks. Unfortunately …

In silico screening and identifying phytoconstituents of Withania somnifera as potent inhibitors of BRCA1 mutants: A therapeutic against breast cancer

SM Panda, U Tripathy - International Journal of Biological …, 2024 - Elsevier
Abstract Breast CAncer gene 1 (BRCA1) is an anti-oncogene that helps the cell repair
damaged DNA and preserve genetic material. BRCA1 also acts as a cell growth suppressor …

Design of a Multiepitope Pan‐Proteomic mRNA Vaccine Construct Against African Swine Fever Virus: A Reverse Vaccinology Approach

EMJS Sira, LE Fajardo, EC Banico… - Veterinary Medicine …, 2025 - Wiley Online Library
African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious
disease with devastating effects on the global pig industry. This warrants the development of …

In silico identification of Nipah virus protein inhibitors from secondary metabolites of medicinal plants using a high-throughput virtual screening approach

JCC de Guzman, ANG Dulay… - Journal of Biomolecular …, 2024 - Taylor & Francis
Abstract The Nipah virus (NiV), a highly pathogenic zoonotic virus of the Paramyxoviridae
family, poses significant threats with its alarming mortality rates and pandemic potential …

[HTML][HTML] Selective protease inhibitors from secondary metabolites of Philippine medicinal plants against porcine epidemic diarrhea virus: A computational veterinary …

JCC de Guzman, ANG Dulay… - Open Veterinary …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Porcine epidemic diarrhea virus (PEDV) is a recurring coronavirus that causes
severe diarrhea in pigs with high mortality and morbidity rates, especially in neonatal pigs …

[PDF][PDF] Bridging One Health: Computational design of a multi-epitope messenger RNA vaccine for cross-species immunization against Nipah virus

EC Banico, EMJS Sira, LE Fajardo, FL Orosco - onehealthjournal.org
Abstract Background and Aim: Nipah virus (NiV) poses a threat to human and animal health,
particularly swine, which serve as primary vectors for human transmission. Despite its …