Human adenoviruses are the most widely used vectors in gene medicine, with applications
ranging from oncolytic therapies to vaccinations, but adenovirus vectors are not without side …

Adenovirus continues to be an important model system for investigating basic aspects of cell
biology. Interactions of several cellular proteins with E1A conserved regions (CR) 1 and 2 …

Viruses employ a variety of strategies to usurp and control cellular activities through the
orchestrated recruitment of macromolecules to specific cytoplasmic or nuclear …

The death-associated protein Daxx found in PML (promyelocytic leukemia protein) nuclear
bodies (PML-NBs) is involved in transcriptional regulation and cellular intrinsic antiviral …

Incoming adenoviruses seize control of cytosolic transport mechanisms to relocate their
genome from the cell periphery to specialized sites in the nucleoplasm. The nucleus is the …

The adenovirus E1B 55K (E1B) protein plays major roles in productive adenoviral infection
and cellular transformation. Interest in E1B increased because of the potential of …

Viruses are intracellular parasites that require host cell functions to reproduce. They must
modify the host cell environment to maximize their replication and avoid the activation of …

Viral oncogenes are responsible for oncogenesis resulting from persistent virus infection.
Although different human tumor viruses express different viral oncogenes and induce …

Death domain–associated protein (Daxx) cooperates with X-linked α-thalassaemia
retardation syndrome protein (ATRX), a putative member of the sucrose non-fermentable 2 …

DNA viruses promote cell cycle progression, stimulate unscheduled DNA synthesis, and
present the cell with an extraordinary amount of exogenous DNA. These insults elicit …