Insight into novel β-cyclodextrin-grafted-poly (N-vinylcaprolactam) nanogel structures as advanced carriers for 5-fluorouracil: Equilibrium behavior and …

HM El-Zeiny, MR Abukhadra, OM Sayed… - Colloids and Surfaces A …, 2020 - Elsevier
Novel β-cyclodextrin-grafted-N-vinylcaprolactam nanogel structures (β-CD-g-PNVCL NG)
were synthesized with different ratios by free radical graft copolymerization in aqueous …

Synthesis of N-vinylcaprolactam and methacrylic acid based hydrogels and investigation of drug release characteristics

B Özkahraman, I Acar, G Güçlü - Polymer Bulletin, 2023 - Springer
In this study, N-vinylcaprolactam (VCL) and methacrylic acid (MAA) based copolymeric
hydrogels with different VCL/MAA molar ratios were produced to develop a temperature …

Synthesis and characterisation of hydrogels based on poly (N-vinylcaprolactam) with diethylene glycol diacrylate

E Halligan, BSH Tie, DM Colbert, M Alsaadi, S Zhuo… - Gels, 2023 - mdpi.com
Poly (N-vinylcaprolactam) is a polymer that is biocompatible, water-soluble, thermally
sensitive, non-toxic, and nonionic. In this study, the preparation of hydrogels based on Poly …

Injectable Thermosensitive Nanocomposites Based on Poly(N-vinylcaprolactam) and Silica Particles for Localized Release of Hydrophilic and Hydrophobic Drugs

LS Ribeiro, RL Sala, TA Robeldo, RC Borra… - Langmuir, 2023 - ACS Publications
The systemic delivery of drugs employed by conventional methods has shown to be less
effective than a localized delivery system. Many drugs have the effectiveness reduced by …

Modulation of the Lower Critical Solution Temperature of Thermoresponsive Poly(N-vinylcaprolactam) Utilizing Hydrophilic and Hydrophobic Monomers

E Halligan, S Zhuo, DM Colbert, M Alsaadi, BSH Tie… - Polymers, 2023 - mdpi.com
Four-dimensional printing is primarily based on the concept of 3D printing technology.
However, it requires additional stimulus and stimulus-responsive materials. Poly-N …

Dual stimuli-responsive nanocarriers via a facile batch emulsion method for controlled release of Rose Bengal

AC Egil, A Carmignani, M Battaglini, BS Sengul… - Journal of Drug Delivery …, 2022 - Elsevier
Stimuli-responsive nanocarriers (SRN) hold great potential as drug delivery systems due to
the ability to tune the release of the drugs by controlling the external stimuli. However, the …

Electrospun poly (NVCL-co-AA) fibers as potential thermo-and pH-sensitive agents for controlled release of hydrophobic drugs

M Sta, DB Tada, SF Medeiros, AM Santos… - Materials Science and …, 2022 - Elsevier
In this study, poly (N-vinylcaprolactam-co-acrylic acid)(poly (NVCL-co-AA)) containing 20
and 30 mol% AA, were used to prepare thermo-and-pH-sensitive fibers containing a …

Cytotoxicity and Biomineralization Potential of Flavonoids Incorporated into PNVCL Hydrogels

GPA Braga, KS Caiaffa, RL Rabelo, VR Santos… - Journal of Functional …, 2023 - mdpi.com
This study aimed to evaluate the effects of flavonoids incorporated into poly (N-
vinylcaprolactam)(PNVCL) hydrogel on cell viability and mineralization markers of …

Design and characterization of PNVCL‐based nanofibers and evaluation of their potential applications as scaffolds for surface drug delivery of hydrophobic drugs

M Sta, G Aguiar, AAJ Forni, SF Medeiros… - Journal of Applied …, 2020 - Wiley Online Library
In this work, nanofiber scaffolds for surface drug delivery applications were obtained by
electrospinning poly (N‐vinylcaprolactam)(PNVCL) and its blends with poly (ε‐caprolactone) …

Multi-responsive γ-methylene-γ-butyrolactone/N-vinyl caprolactam copolymers involving pH-dependent reversible lactonization

Z Wang, A Debuigne - Polymer Chemistry, 2022 - pubs.rsc.org
Poly (N-vinyl caprolactam) is one of the most popular thermo-responsive polymers used in
the biomedical field. For application purposes, its transition temperature can be adjusted by …