A three-layer perspective on miRNA regulation in β cell inflammation

S Auddino, E Aiello, GE Grieco, F Dotta… - Trends in Endocrinology …, 2024 - cell.com
MicroRNAs (miRNAs) are noncoding RNA molecules that regulate gene expression post-
transcriptionally and influence numerous biological processes. Aberrant miRNA expression …

Exploring new frontiers in type 1 diabetes through advanced mass-spectrometry-based molecular measurements

S Sarkar, X Zheng, GC Clair, YM Kwon, Y You… - Trends in Molecular …, 2024 - cell.com
Abstract Type 1 diabetes (T1D) is a devastating autoimmune disease for which advanced
mass spectrometry (MS) methods are increasingly used to identify new biomarkers and …

Free fatty acids accelerate β-cell death in type 1 diabetes

EC Elliott, S Sarkar, L Bramer, M Burnet, YM Kim, X Yi… - medRxiv, 2024 - medrxiv.org
Type 1 diabetes (T1D) results from autoimmune destruction of the insulin-producing
pancreatic beta cells. The body lipid metabolism is strongly regulated during this process but …