Dexamethasone: insights into pharmacological aspects, therapeutic mechanisms, and delivery systems

VS Madamsetty, R Mohammadinejad… - ACS biomaterials …, 2022 - ACS Publications
Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …

[HTML][HTML] Monitoring dexamethasone skin biodistribution with ex vivo MALDI-TOF mass spectrometry imaging and confocal Raman microscopy

E Pena-Rodríguez, T García-Berrocoso… - International Journal of …, 2023 - Elsevier
Two of the most promising techniques in terms of ex vivo skin imaging and quantifying are
confocal Raman microscopy and MALDI-TOF mass spectrometry imaging (MALDI-TOF MSI) …

[HTML][HTML] Lipid extract from Black Soldier Fly larvae: A high value excipient for solid lipid nanoparticles tailored to tackle atopic dermatitis

C Almeida, R Roque, J Vieira, A Júlio, N Saraiva… - International Journal of …, 2024 - Elsevier
Atopic dermatitis (AD) is a chronic inflammatory skin disorder with a complex pathogenesis
involving epidermal barrier dysfunction and aberrant lipid composition, particularly …

The physicochemical, biopharmaceutical, and in vitro efficacy properties of freeze-dried dexamethasone-loaded lipomers

E Pena-Rodríguez, A Mata-Ventosa, L Garcia-Vega… - Pharmaceutics, 2021 - mdpi.com
Dexamethasone-loaded polymer hybrid nanoparticles were developed as a potential tool to
treat alopecia areata due to their follicular targeting ability. Freeze drying (FD) is a common …

Anthocyanin extract from black rice attenuates chronic inflammation in DSS-induced colitis mouse model by modulating the gut microbiota

Y Li, F Yuan, X He, S Fu, B Fan - Open Chemistry, 2023 - degruyter.com
There is substantial evidence for the probiotic activity of anthocyanins, but the relationship
between anthocyanins involved in the regulation of microbiota and intestinal inflammation …

Advanced Skin Antisepsis: Application of UVA-Cleavable Hydroxyethyl Starch Nanocapsules for Improved Eradication of Hair Follicle-Associated Microorganisms

L Busch, AM Hanuschik, Y Avlasevich, K Darm… - Pharmaceutics, 2023 - mdpi.com
Hair follicles constitute important drug delivery targets for skin antisepsis since they
contain≈ 25% of the skin microbiome. Nanoparticles are known to penetrate deeply into …

Repurposing Disulfiram as an Antifungal Agent: Development of a New Disulfiram Vaginal Mucoadhesive Gel

M Lajarin-Reinares, I Naveira-Souto, M Mallandrich… - Pharmaceutics, 2023 - mdpi.com
Alternative formulations need to be developed to improve the efficacy of treatments
administered via the vaginal route. Mucoadhesive gels with disulfiram, a molecule that was …

Insect larvae oil: a high value excipient for lipid-based nanocarriers to tackle atopic dermatitis

CJ Almeida, R Roque, J Vieira, A Júlio, N Saraiva… - 2024 - chemrxiv.org
Atopic dermatitis (AD) is a chronic inflammatory skin disorder with a complex pathogenesis
involving epidermal barrier dysfunction and aberrant lipid composition, particularly …

Preclinical Evaluation of Lipid-Based Nanosystems

AC Silva, JM Sousa Lobo - Pharmaceutics, 2021 - mdpi.com
The use of lipid-based nanosystems, including lipid nanoparticles (solid lipid nanoparticles—
SLN, and nanostructured lipid carriers—NLC), nanoemulsions, and liposomes, among …