Chemosensory neurons translate perception of external chemical cues, including odorants,
tastants, and pheromones, into information that drives attraction or avoidance motor …

New technologies in neuroscience generate reams of data at an exponentially increasing
rate, spurring the design of very-large-scale data-mining initiatives. Several supranational …

Comprehensively resolving neuronal identities in whole-brain images is a major challenge.
We achieve this in C. elegans by engineering a multicolor transgene called NeuroPAL (a …

The ability to acquire large-scale recordings of neuronal activity in awake and unrestrained
animals is needed to provide new insights into how populations of neurons generate animal …

Variability is a prominent feature of behavior and is an active element of certain behavioral
strategies. To understand how neuronal circuits control variability, we examined the …

Neurons in Caenorhabditis elegans and other nematodes have been thought to lack
classical action potentials. Unexpectedly, we observe membrane potential spikes with …

Caenorhabditis elegans lives in a complex habitat in which they routinely experience large
fluctuations in temperature, and encounter physical obstacles that vary in size and …

The performance of complex networks, like the brain, depends on how effectively their
elements communicate. Despite the importance of communication, it is virtually unknown …

The optimal foraging strategy in a given environment depends on the number of competing
individuals and their behavioural strategies. Little is known about the genes and neural …

Little is known about how animals integrate multiple sensory inputs in natural environments
to balance avoidance of danger with approach to things of value. Furthermore, the …