[HTML][HTML] Proton pump inhibitors therapy and risk of Clostridium difficile infection: Systematic review and meta-analysis

A Trifan, C Stanciu, I Girleanu, OC Stoica… - World journal of …, 2017 - ncbi.nlm.nih.gov
AIM To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs)
therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a …

Probiotics are effective at preventing Clostridium difficile-associated diarrhea: a systematic review and meta-analysis

CSM Lau, RS Chamberlain - International journal of general …, 2016 - Taylor & Francis
Introduction Clostridium difficile infection (CDI) is the leading cause of antibiotic-associated
diarrhea. CDI has increased in incidence and severity over the past decade, and is a …

Updated meta-analysis of controlled observational studies: proton-pump inhibitors and risk of Clostridium difficile infection

F Cao, CX Chen, M Wang, HR Liao, MX Wang… - Journal of Hospital …, 2018 - Elsevier
Attention has recently been directed toward a plausible link between Clostridium difficile
infection (CDI) and proton-pump inhibitors (PPIs). However, the results of studies on the …

Hospital ward antibiotic prescribing and the risks of Clostridium difficile infection

K Brown, K Valenta, D Fisman, A Simor… - JAMA internal …, 2015 - jamanetwork.com
Importance Only a portion of hospital-acquiredClostridium difficileinfections can be traced
back to source patients identified as having symptomatic disease. Antibiotic exposure is the …

Probiotics for the prevention of antibiotic-associated diarrhea

K Kopacz, S Phadtare - Healthcare, 2022 - mdpi.com
Several communities have started using probiotic-rich fermented foods as therapeutic
options with presumed medicinal powers. We now know the importance of microbiome …

Use of ribaxamase (SYN-004), a β-lactamase, to prevent Clostridium difficile infection in β-lactam-treated patients: a double-blind, phase 2b, randomised placebo …

JF Kokai-Kun, T Roberts, O Coughlin, C Le… - The Lancet infectious …, 2019 - thelancet.com
Summary Background Infections with Clostridium difficile are a health threat, yet no products
are currently licensed for prevention of primary C difficile infections. Intravenous β-lactam …

Stress ulcer prophylaxis

JF Barletta, JJ Bruno, MS Buckley… - Critical care medicine, 2016 - journals.lww.com
Objectives: Stress ulcer prophylaxis is commonly administered to critically ill patients for the
prevention of clinically important stress-related mucosal bleeding from the upper …

Assessing the risk of hospital-acquired Clostridium difficile infection with proton pump inhibitor use: a meta-analysis

V Arriola, J Tischendorf, J Musuuza… - infection control & …, 2016 - cambridge.org
BACKGROUNDClostridium difficile is the principal infectious cause of antibiotic-associated
diarrhea and accounts for 12% of hospital-acquired infections. Recent literature has shown …

Magnitude and direction of the association between Clostridium difficile infection and proton pump inhibitors in adults and pediatric patients: a systematic review and …

T Oshima, L Wu, M Li, H Fukui, J Watari… - Journal of …, 2018 - Springer
Background Clostridium difficile infection (CDI) is a cause of increased morbidity and health
care costs among hospitalized patients. Proton pump inhibitors (PPIs) are mainly used for …

Acid Suppression Therapy Does Not Predispose to Clostridium difficile Infection: The Case of the Potential Bias

L Novack, S Kogan, L Gimpelevich, M Howell, A Borer… - PLoS …, 2014 - journals.plos.org
Objective An adverse effect of acid-suppression medications on the occurrence of
Clostridium difficile infection (CDI) has been a common finding of many, but not all studies …