Personalised therapeutic approaches to glioblastoma: A systematic review

OD Mowforth, J Brannigan, M El Khoury… - Frontiers in …, 2023 - frontiersin.org
Introduction Glioblastoma is the most common and malignant primary brain tumour with
median survival of 14.6 months. Personalised medicine aims to improve survival by …

[HTML][HTML] Tumor-associated microenvironment, PD-L1 expression and their relationship with immunotherapy in glioblastoma, IDH-wild type: A comprehensive review …

G Broggi, G Angelico, J Farina, G Tinnirello… - … -Research and Practice, 2024 - Elsevier
Although novel knowledge has been acquired on the molecular landscape of glioblastoma
(GBM), a relatively few steps forward have been made regarding its therapy. With the …

Emerging trends in post-translational modification: Shedding light on Glioblastoma multiforme

S Kumari, R Gupta, RK Ambasta, P Kumar - Biochimica et Biophysica Acta …, 2023 - Elsevier
Recent multi-omics studies, including proteomics, transcriptomics, genomics, and
metabolomics have revealed the critical role of post-translational modifications (PTMs) in the …

Glioblastoma mesenchymal subtype enhances antioxidant defence to reduce susceptibility to ferroptosis

S D'Aprile, S Denaro, A Lavoro, S Candido… - Scientific Reports, 2024 - nature.com
Glioblastoma (GBM) represents an aggressive brain tumor, characterized by intra-and inter-
tumoral heterogeneity and therapy resistance, leading to unfavourable prognosis. An …

Microenvironmental regulation of tumor-associated neutrophils in malignant glioma: from mechanism to therapy

J Wen, D Liu, H Zhu, K Shu - Journal of Neuroinflammation, 2024 - Springer
Glioma is the most common primary intracranial tumor in adults, with high incidence,
recurrence, and mortality rates. Tumor-associated neutrophils (TANs) are essential …

[HTML][HTML] Effect of the Mediterranean Diet (MeDi) on the Progression of Retinal Disease: A Narrative Review

O Sbai, F Torrisi, FP Fabrizio, G Rabbeni, L Perrone - Nutrients, 2024 - mdpi.com
Worldwide, the number of individuals suffering from visual impairment, as well as those
affected by blindness, is about 600 million and it will further increase in the coming decades …

GBM Immunotherapy: Macrophage Impacts

N Loginova, D Aniskin, P Timashev… - Immunological …, 2024 - Taylor & Francis
Background Glioblastoma (GBM) is an extremely aggressive form of brain tumor with low
survival rates. Current treatments such as chemotherapy, radiation, and surgery are …

Digital Pathology: A Comprehensive Review of Open-Source Histological Segmentation Software

AM Pavone, AG Giannone, D Cabibi, S D'Aprile… - …, 2024 - mdpi.com
In the era of digitalization, the biomedical sector has been affected by the spread of artificial
intelligence. In recent years, the possibility of using deep and machine learning methods for …

Comunicazione intercellulare e riprogrammazione del microambiente tumorale nella risposta patofisiologia del glioblastoma alla radioterapia

C Alberghina - 2023 - tesidottorato.depositolegale.it
Tumor microenvironment (TME), composed by a milieu of stromal and immune cells, is one
of the critical players in glioblastoma (GBM) progression and heterogeneity. GBM …

[PDF][PDF] Intercellular communication and tumor microenvironment rewiring in glioblastoma pathophysiological response to radiotherapy

C ALBERGHINA - iris.unict.it
L'insorgenza e la progressione del glioblastoma (GBM) è supportata da un ampio range di
fattori che influenzano lo stato metabolico, il setting genetico ed epigenetico del tumore e …