Solute carrier (SLCs) transporters mediate the transport of a broad range of solutes across
biological membranes. Dysregulation of SLCs has been associated with various …

The major transmembrane protein of the red blood cell, known as band 3, AE1, and
SLC4A1, has two main functions: 1) catalysis of Cl−/HC O 3− exchange, one of the steps in …

Rapid flip-flop of phospholipids across the two leaflets of biological membranes is crucial for
many aspects of cellular life. The transport proteins that facilitate this process are classified …

Excitatory amino acid transporters (EAATs) are important in many physiological processes
and crucial for the removal of excitatory amino acids from the synaptic cleft. Here, we …

py-MCMD, an open-source Python software, provides a robust workflow layer that manages
communication of relevant system information between the simulation engines NAMD and …

Solute carrier family 4 (SLC4) transporters mediate the transmembrane transport of HCO 3−,
CO 3 2−, and Cl− necessary for pH regulation, transepithelial H+/base transport, and ion …

Transporters mediate the uptake of solutes, metabolites and drugs across the cell
membrane. The eukaryotic FurE nucleobase/H+ symporter of Aspergillus nidulans has been …

P-glycoprotein (Pgp) is a major efflux pump in humans, overexpressed in a variety of
cancers and associated with the development of multi-drug resistance. Allosteric modulation …

Protein transporters not only have essential functions in regulating the transport of
endogenous substrates and remote communication between organs and organisms, but …

Posttranslational modifications (PTMs) are an integral component to how cells respond to
perturbation. While experimental advances have enabled improved PTM identification …