Focal adhesion kinase (FAK), a nonreceptor cytoplasmic tyrosine kinase, is a vital
participant in primary cellular functions, such as proliferation, survival, migration, and …

Focal adhesion kinase (FAK; also known as PTK2) was discovered three decades ago and
is now recognised as a key player in the regulation of cell–matrix adhesion and …

In recent years, there have been multiple breakthroughs in cancer immunotherapy, with
immune checkpoint inhibitors becoming the most promising treatment strategy. However …

Programmed cell death protein-1 (PD-1), also called CD279, is coded by the PDCD1 gene
and is constitutively expressed on the surface of immune cells. As a receptor and immune …

As a common malignant tumor among women, ovarian cancer poses a serious threat to their
health. This study demonstrates that long non-coding RNA NRSN2-AS1 is over-expressed …

Focal adhesion kinase (FAK; encoded by PTK2) was discovered over 30 years ago as a
cytoplasmic protein tyrosine kinase that is localized to cell adhesion sites, where it is …

Immune checkpoints (ICs), also referred to as co-inhibitory receptors (IRs), are essential for
regulating immune cell function to maintain tolerance and prevent autoimmunity. IRs, such …

The dense desmoplastic and fibrotic stroma is a characteristic feature of pancreatic ductal
adenocarcinoma (PDAC), regulating disease progression, metastasis and response to …

Simple Summary Ovarian cancer (OC) is the most lethal gynecological malignancy with a
five-year survival rate of 47%, followed by cervical cancer (66%), and uterine cancer (81%) …

CD155, also known as the poliovirus receptor, is an adhesion molecule often overexpressed
in tumors of different origins where it promotes cell migration and proliferation. In addition to …