Hearing loss stands as the most prevalent sensory deficit among humans, posing a
significant global health challenge. Projections indicate that by 2050, approximately 10% of …

Hereditary deafness is the most prevalent sensory deficit disorder, with over 100 identified
deafness‐related genes. Clinical treatment options are currently limited to external devices …

Usher syndrome type 1F (USH1F), resulting from mutations in the protocadherin-15
(PCDH15) gene, is characterized by congenital lack of hearing and balance, and …

Usher syndrome type 1F (USH1F), characterized by congenital lack of hearing and balance
and progressive loss of vision, is caused by mutations in the PCDH15 gene. In the …

Up to 1.5 billion people worldwide suffer from various forms of hearing loss, with an
additional 1.1 billion people at risk from various insults such as increased consumption of …

Gene therapies for hearing loss are expected to enter clinical trials in the immediate future.
To provide referral for appropriate trials and counseling regarding benefits of genetic …

Abstract Adeno‐associated virus (AAV)‐based therapies are recognized as one of the most
potent next‐generation treatments for inherited and genetic diseases. However, several …

Deafness is the most common form of sensory impairment in humans and frequently caused
by defects in hair cells of the inner ear. Here we demonstrate that in male mice which model …

Usher syndrome type 1F (USH1F), resulting from mutations in the protocadherin-15
(PCDH15) gene, is characterized by congenital lack of hearing and balance, and …

About one in 500 children is born with significant hearing impairment, and at least half of the
cases have genetic causes (1). Two-or threefold more children have normal hearing at birth …