Salmonella enterica serovars Typhimurium and Typhi as model organisms: Revealing paradigm of host-pathogen interactions

P Garai, DP Gnanadhas, D Chakravortty - Virulence, 2012 - Taylor & Francis
The lifestyle of intracellular pathogens has always questioned the skill of a microbiologist in
the context of finding the permanent cure to the diseases caused by them. The best tool …

A review of using mathematical modeling to improve our understanding of bacteriophage, bacteria, and eukaryotic interactions

KM Styles, AT Brown, AP Sagona - Frontiers in Microbiology, 2021 - frontiersin.org
Phage therapy, the therapeutic usage of viruses to treat bacterial infections, has many
theoretical benefits in the 'post antibiotic era.'Nevertheless, there are currently no approved …

Diamond relaxometry as a tool to investigate the free radical dialogue between macrophages and bacteria

K Wu, L Nie, AC Nusantara, W Woudstra, T Vedelaar… - ACS …, 2023 - ACS Publications
Although free radicals, which are generated by macrophages play a key role in antimicrobial
activities, macrophages sometimes fail to kill Staphylococcus aureus (S. aureus) as bacteria …

Phagocytosis dynamics depends on target shape

D Paul, S Achouri, YZ Yoon, J Herre, CE Bryant… - Biophysical journal, 2013 - cell.com
A complete understanding of phagocytosis requires insight into both its biochemical and
physical aspects. One of the ways to explore the physical mechanism of phagocytosis is to …

Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium

X Wang-Kan, JMA Blair, B Chirullo, J Betts… - MBio, 2017 - Am Soc Microbiol
AcrAB-TolC is the paradigm resistance-nodulation-division (RND) multidrug resistance
efflux system in Gram-negative bacteria, with AcrB being the pump protein in this complex …

Highly efficient phototheranostics of macrophage-engulfed Gram-positive bacteria using a NIR luminogen with aggregation-induced emission characteristics

MMS Lee, D Yan, JHC Chau, H Park, CCH Ma… - Biomaterials, 2020 - Elsevier
Although phagocytosis serves as the front line to attack invading pathogens, its low bacterial
encounter and killing rates leads to an ineffective bactericidal output. In view of this …

Manipulation of autophagy in phagocytes facilitates Staphylococcus aureus bloodstream infection

KM O'Keeffe, MM Wilk, JM Leech, AG Murphy… - Infection and …, 2015 - Am Soc Microbiol
The capacity for intracellular survival within phagocytes is likely a critical factor facilitating
the dissemination of Staphylococcus aureus in the host. To date, the majority of work on S …

Actin polymerization as a key innate immune effector mechanism to control Salmonella infection

SM Man, A Ekpenyong… - Proceedings of the …, 2014 - National Acad Sciences
Salmonellosis is one of the leading causes of food poisoning worldwide. Controlling
bacterial burden is essential to surviving infection. Nucleotide-binding oligomerization …

How cells engulf: a review of theoretical approaches to phagocytosis

DM Richards, RG Endres - Reports on progress in physics, 2017 - iopscience.iop.org
Phagocytosis is a fascinating process whereby a cell surrounds and engulfs particles such
as bacteria and dead cells. This is crucial both for single-cell organisms (as a way of …

Oral mRNA vaccines against infectious diseases-A bacterial perspective

V Jawalagatti, P Kirthika, JH Lee - Frontiers in Immunology, 2022 - frontiersin.org
The mRNA vaccines from Pfizer/BioNTech and Moderna were granted emergency approval
in record time in the history of vaccinology and played an instrumental role in limiting the …