Low-income and middle-income countries (LMICs) bear a disproportionately high burden of
the global morbidity and mortality caused by chronic respiratory diseases (CRDs), including …

An estimated 58 million people have survived tuberculosis since 2000, yet many of them will
suffer from post-tuberculosis lung disease (PTLD). PTLD results from a complex interplay …

TB affects around 10.6 million people each year and there are now around 155 million TB
survivors. TB and its treatments can lead to permanently impaired health and wellbeing. In …

Background A substantial proportion of tuberculosis patients remain with pulmonary
symptoms and reduced physical capacity despite successful treatment. We performed a …

Background People who survive tuberculosis face clinical and societal consequences after
recovery, including increased risks of recurrent tuberculosis, premature death, reduced lung …

Rationale: There is growing concern that post–tuberculosis disease (TB) sequelae and
morbidity are substantial, but no studies have controlled for preexisting factors before …

Following infection with Mycobacterium tuberculosis, the causative agent of tuberculosis
(TB), most human hosts are able to contain the infection and avoid progression to active TB …

Background Emerging evidence suggests that after completion of treatment for tuberculosis
(TB) a significant proportion of patients experience sequelae. However, there is limited …

BACKGROUND Matrix metalloproteinases (MMPs) are key regulators of tissue destruction in
tuberculosis (TB) and may be targets for host-directed therapy. We conducted a phase II …

We are facing an unprecedented pandemic. A quarter of the world's population is infected
and, between 2020 and 2021, it is predicted that 10 million people will have fallen ill, 3 …