Applications of resting-state functional connectivity to neurodegenerative disease

J Zhou, S Liu, KK Ng, J Wang - Neuroimaging Clinics, 2017 - neuroimaging.theclinics.com
Neurodegeneration, characterized by gradual and selective spreading of pathologic
changes in a target brain network, leads to specific behavioral and cognitive dysfunctions …

Brain atrophy and white matter hyperintensities are independently associated with plasma neurofilament light chain in an Asian cohort of cognitively impaired patients …

JR Chong, S Hilal, NJ Ashton… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Plasma neurofilament light chain (NfL) is a potential biomarker for
neurodegeneration in Alzheimer's disease (AD), ischemic stroke, and non‐dementia cohorts …

Circuit quantization in the presence of time-dependent external flux

X You, JA Sauls, J Koch - Physical Review B, 2019 - APS
Circuit quantization links a physical circuit to its corresponding quantum Hamiltonian. The
standard quantization procedure generally assumes any external magnetic flux to be static …

Abnormal anatomical Rich-Club organization and structural–functional coupling in mild cognitive impairment and Alzheimer's disease

R Cao, X Wang, Y Gao, T Li, H Zhang… - Frontiers in …, 2020 - frontiersin.org
Emerging research indicates interruptions in the wiring organization of the brain network in
Mild cognitive impairment (MCI) and Alzheimer's disease (AD). Due to the important role of …

Distinct white matter microstructural abnormalities and extracellular water increases relate to cognitive impairment in Alzheimer's disease with and without …

F Ji, O Pasternak, S Liu, YM Loke, BL Choo… - Alzheimer's Research & …, 2017 - Springer
Background Mixed vascular and neurodegenerative dementia, such as Alzheimer's disease
(AD) with concomitant cerebrovascular disease, has emerged as the leading cause of age …

MRI-based classification models in prediction of mild cognitive impairment and dementia in late-life depression

AK Lebedeva, E Westman, T Borza… - Frontiers in aging …, 2017 - frontiersin.org
Objective: Late-life depression (LLD) is associated with development of different types of
dementia. Identification of LLD patients, who will develop cognitive decline, ie, the early …

Alterations in a cross-hemispheric circuit associates with novelty discrimination deficits in mouse models of neurodegeneration

C Adaikkan, J Wang, K Abdelaal, SJ Middleton… - Neuron, 2022 - cell.com
A major pathological hallmark of neurodegenerative diseases, including Alzheimer's, is a
significant reduction in the white matter connecting the two cerebral hemispheres, as well as …

Alterations in brain network topology and structural-functional connectome coupling relate to cognitive impairment

J Wang, R Khosrowabadi, KK Ng, Z Hong… - Frontiers in Aging …, 2018 - frontiersin.org
According to the network-based neurodegeneration hypothesis, neurodegenerative
diseases target specific large-scale neural networks, such as the default mode network, and …

Preconditioning with partial caloric restriction confers long-term protection against grey and white matter injury after transient focal ischemia

J Zhang, W Zhang, X Gao, Y Zhao… - Journal of Cerebral …, 2019 - journals.sagepub.com
Caloric restriction (CR) has been extensively examined as a preventative strategy against
aging and various diseases, but CR effects on cerebral ischemia are largely unknown. We …

White matter network damage mediates association between cerebrovascular disease and cognition

S Hilal, S Liu, TY Wong, H Vrooman… - Journal of Cerebral …, 2021 - journals.sagepub.com
To determine whether white matter network disruption mediates the association between
MRI markers of cerebrovascular disease (CeVD) and cognitive impairment. Participants (n …