Hydrazine-related chemicals (HRCs) with carcinogenic and neurotoxic potential are found in
certain mushrooms and plants used for food and in products employed in various industries …

Biomolecular condensates are membraneless organelles (MLOs) that form dynamic,
chemically distinct subcellular compartments organizing macromolecules such as proteins …

Converging evidence demonstrates that microRNAs (miRNAs) play an important role in the
etiology of cognitive impairment. Thus, we aim to:(i) identify the molecular mechanisms of …

Alzheimer's disease (AD) is the most prevalent form of dementia in the old adult and
characterized by progressive cognitive decline and neuronal damage. The mammalian …

During the past two decades, induced pluripotent stem cells (iPSCs) have been widely used
to study human neural development and disease. Especially in the field of Alzheimer's …

Our understanding of Alzheimer's disease (AD) pathogenesis has developed with several
hypotheses over the last 40 years, including the Amyloid and Tau hypotheses. More …

Introduction Alzheimer's disease remains the most common neurodegenerative disorder,
depicted mainly by memory loss and the presence in the brain of senile plaques and …

The protein p53 is the main human tumor suppressor. Since its discovery, extensive
research has been conducted, which led to the general assumption that the purview of p53 …

Early diagnosis of Alzheimer's disease (AD) is a crucial starting point in disease
management. Blood-based biomarkers could represent a considerable advantage in …

Context Ursolic acid (UA) and acteoside (ATS) are important active components that have
been used to treat Alzheimer's disease (AD) because of their neuroprotective effects, but the …