Zebrafish (Danio rerio) is emerging as an increasingly successful model for translational
research on human neurological disorders. In this review, we appraise the high degree of …

Risk for Alzheimer's disease (AD) is associated with age-related loss of sex steroid
hormones in both women and men. In post-menopausal women, the precipitous depletion of …

Alzheimer's disease (AD) is the most common type of dementia. Its diagnosis and
progression detection have been intensively studied. Nevertheless, research studies often …

Alzheimerβs disease (AD) is a multifactorial neurodegenerative disorder with several target
proteins contributing to its aetiology. Pathological, genetic, biochemical, and modeling …

Neurotrophic factors (NTF) are small, versatile proteins that maintain survival and function to
specific neuronal populations. In general, the axonal transport of NTF is important as not all …

A promising strategy to delay and perhaps prevent Alzheimer's disease (AD) is to identify the
age-related changes that put the brain at risk for the disease. A significant normal age …

Abstract Beta-amyloid (β-A) peptides are potential biomarkers to monitor Alzheimer's
diseases (AD) for diagnostic purposes. Increased β-A level is neurotoxic and induces …

Currently, the 'amyloid hypothesis' is the most widely accepted explanation for the
pathogenesis of Alzheimer's disease (AD). According to this hypothesis, altered metabolism …

Alzheimer's disease (AD) is the most common neurodegenerative disorder, affecting millions
of people worldwide. Apart from age, the major risk factor identified so far for the sporadic …

Several prospective cohort studies have reported an association between higher levels of
physical activity and decreased risk of cognitive decline and dementia, years later. To …