Cellular hypomethylation is associated with impaired nitric oxide production by cultured human endothelial cells

M Barroso, MS Rocha, R Esse, I Gonçalves, AQ Gomes… - Amino Acids, 2012 - Springer
Hyperhomocysteinemia (HHcy) is a risk factor for vascular disease, but the underlying
mechanisms remain incompletely defined. Reduced bioavailability of nitric oxide (NO) is a …

Asymmetric dimethylarginine in adults with cystathionine β-synthase deficiency

MS Rocha, T Teerlink, MCH Janssen, LAJ Kluijtmans… - Atherosclerosis, 2012 - Elsevier
In hyperhomocysteinemia (HHcy), an independent risk factor for cardiovascular diseases,
endothelial dysfunction due to reduced bioavailability of nitric oxide is a consistent finding …

[HTML][HTML] Deciphering protein arginine methylation in mammals

R Esse, P Leandro, I Rivera, IT de Almeida… - … -From DNA, RNA and …, 2012 - intechopen.com
The myriad of different post-translation modifications (PTMs) of proteins augments the
information encoded by the human genome, from about 25,000 genes to over 1 million …

[PDF][PDF] Cellular Hypomethylation is Associated with Impaired Nitric Oxide Production by Cultured Human Endothelial Cells

OP by Cultured - … Endothelial Dysfunction and Activation: a Role for …, 2015 - repositorio.ul.pt
Hyperhomocysteinemia (HHcy) is a risk factor for vascular disease, but the underlying
mechanisms remain incompletely defined. Reduced bioavailability of nitric oxide (NO) is a …

[PDF][PDF] S-adenosylhomocysteine increases DDAH activity in human cultured endothelial cells, via a non-DNA dependent methylathion pathway

MS Rocha, T Teerlink, P Koolwijk, YM Smulders… - … of Homocysteine, Nitric … - Citeseer
Hyperhomocysteinemia, an independent risk factor for cardiovascular diseases, correlates
with reduced nitric oxide (NO) bioavailability. Increased levels of asymmetric …

Diets inducing Hyperhomocysteinemia affect global DNA methylation in a tissue-specific manner

MS Rocha, K Vis, R Esse, A Imbard… - … of Homocysteine, Nitric … - search.proquest.com
The pathophysiology of homocysteine (Hcy) may be attributed to accumulation of its
precursor S-adenosylhomocysteine (AdoHcy), which as a strong demethylating agent, may …