Pathway enrichment analysis has become a widely used knowledge-based approach for the
interpretation of biomedical data. Its popularity has led to an explosion of both enrichment …

Advances in high-throughput technologies have enhanced our ability to describe microbial
communities as they relate to human health and disease. Alongside the growth in …

Abstract Pathway Data Integration Portal (PathDIP) is an integrated pathway database that
was developed to increase functional gene annotation coverage and reduce bias in …

Translational research requires data at multiple scales of biological organization.
Advancements in sequencing and multi-omics technologies have increased the availability …

Background Precision medicine in oncology relies on rapid associations between patient-
specific variations and targeted therapeutic efficacy. Due to the advancement of genomic …

Abstract PathBank (https://pathbank. org) and its predecessor database, the Small Molecule
Pathway Database (SMPDB), have been providing comprehensive metabolite pathway …

The “RNA world” represents a novel frontier for the study of fundamental biological
processes and human diseases and is paving the way for the development of new drugs …

Next-generation sequencing (NGS) of whole genomes and exomes is a powerful tool in
biomedical research and clinical diagnostics. However, the vast amount of data produced by …

Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infection is a leading
cause of pneumonia and death. The aim of this investigation is to identify the key genes in …

Thousands of pathway diagrams are published each year as static figures inaccessible to
computational queries and analyses. Using a combination of machine learning, optical …