Multiciliated cells are epithelial cells that are in contact with bodily fluids and are required for
the proper function of major organs including the brain, the respiratory system and the …

The generation of organismal form—morphogenesis—arises from forces produced at the
cellular level. In animal cells, much of this force is produced by the actin cytoskeleton. Here …

Primary cilia are microtubule-based organelles that extend from the apical surface of most
mammalian cells, forming when the basal body (derived from the mother centriole) docks at …

Cell motility is a widespread biological property that is best understood in the context of
individual cell migration. Indeed, studies of migration in culture have provided tremendous …

During embryonic development, regeneration, and homeostasis, cells have to migrate and
physically integrate into the target tissues where they ultimately execute their function. While …

Tricellular contacts are the places where three cells meet. In vertebrate epithelial cells,
specialized structures called tricellular tight junctions (tTJs) and tricellular adherens …

The mammalian hearing organ, the organ of Corti, is one of the most organized tissues in
mammals. It contains a precisely positioned array of alternating sensory hair cells (HCs) and …

Multiciliated cells (MCC) project dozens to hundreds of motile cilia from the cell surface to
generate fluid flow across epithelial surfaces or turbulence to promote the transport of …

In vertebrates, multiciliated cells (MCCs) are terminally differentiated cells that line the
airway tracts, brain ventricles, and reproductive ducts. Each MCC contains dozens to …

The c-Jun N-terminal kinase (JNK) regulates various important physiological processes.
Although the JNK pathway has been under intense investigation for over 20 yr, its …