Understanding and controlling peptide aggregation are critical due to its neurotoxic
implications. However, structural information about the key intermediates, the oligomers, is …

In this review, we focus on the biophysical and structural aspects of the oligomeric states of
physiologically intrinsically disordered proteins and peptides tau, amyloid-β and α-synuclein …

The aggregation of the proteins tau and amyloid-β is a salient feature of Alzheimer's
disease, the most common form of neurodegenerative disorders. Upon aggregation …

Protein aggregation is involved in many human diseases, but characterizing the sizes and
shapes of intermediate oligomers (∼ 10–100 nm) that are important to the formation of …

Background Alzheimer's disease (AD) is a neurodegenerative disorder with a very long
duration, posing a serious threat to people's life and health. To date, no medicine that can …