Reporter parasite lines: valuable tools for the study of Plasmodium biology

Y Miyazaki, S Miyazaki - Trends in Parasitology, 2024 - cell.com
The human malaria parasite Plasmodium falciparum causes the most severe form of malaria
in endemic regions and is transmitted via mosquito bites. To better understand the biology of …

Plasmodium falciparum gametocytes display global chromatin remodelling during sexual differentiation

MD Jeninga, J Tang, SA Selvarajah, AG Maier… - BMC biology, 2023 - Springer
Background The protozoan malaria parasite Plasmodium falciparum has a complex life
cycle during which it needs to differentiate into multiple morphologically distinct life forms. A …

The Plasmodium falciparum histone methyltransferase PfSET10 is dispensable for the regulation of antigenic variation and gene expression in blood-stage parasites

M Wyss, A Kanyal, I Niederwieser, R Bartfai, TS Voss - mSphere, 2024 - journals.asm.org
The malaria parasite Plasmodium falciparum employs antigenic variation of the virulence
factor P. falciparum erythrocyte membrane protein 1 (PfEMP1) to escape adaptive immune …

The three Plasmodium falciparum Aurora-related kinases display distinct temporal and spatial associations with mitotic structures in asexual blood stage parasites …

M Wyss, BT Thommen, J Kofler, E Carrington… - Msphere, 2024 - journals.asm.org
Aurora kinases are crucial regulators of mitotic cell cycle progression in eukaryotes. The
protozoan malaria parasite Plasmodium falciparum replicates via schizogony, a specialized …

Harnessing cholesterol uptake of malaria parasites for therapeutic applications

M Fraser, B Curtis, P Phillips, PA Yates… - EMBO Molecular …, 2024 - embopress.org
Parasites, such as the malaria parasite P. falciparum, are critically dependent on host
nutrients. Interference with nutrient uptake can lead to parasite death and, therefore, serve …

Analysis of sex-specific lipid metabolism of Plasmodium falciparum points to the importance of sphingomyelin for gametocytogenesis

MC Ridgway, D Cihalova, SHJ Brown… - Journal of cell …, 2022 - journals.biologists.com
Male and female Plasmodium falciparum gametocytes are the parasite lifecycle stage
responsible for transmission of malaria from the human host to the mosquito vector. Not only …

CRISPR-Cas9-based method for isolating microgametes of Eimeria tenella

Z Qu, Z Gong, JS Olajide, J Wang, J Cai - Veterinary Parasitology, 2024 - Elsevier
Eimeria tenella infections are known to cause severe caecal damage and death of the
infected chicken. Gamogony is an essential stage in E. tenella life cycle and in the …

Sex-specific separation of Plasmodium falciparum gametocyte populations

MC Ridgway, D Cihalova, AG Maier - Bio-protocol, 2021 - bio-protocol.org
Plasmodium falciparum is a unicellular eukaryotic parasite that causes malaria in humans.
The parasite is spread by Anopheles mosquitoes after ingestion of sexual stage parasites …

[PDF][PDF] Plasmodium Gametocyte Biology and the Interrelation Between Host and Mosquito Infectivity

AN Roberds - 2022 - apps.dtic.mil
Over the past several decades, malaria/HIV-1 co-infection has become a significant global
public health problem in co-endemic areas of the world. The geographical overlap between …

Epigenetic Mechanisms in Gametocytogenesis of Plasmodium falciparum

M Jeninga - 2023 - search.proquest.com
Malaria is caused by Plasmodium spp. parasites that are transmitted by Anopheles
mosquitoes. During the life cycle of P. falciparum, the parasites undergo multiple …