Imaging the interior of living bodies with light may assist in the diagnosis and treatment of a
number of clinical problems, which include the early detection of tumors and hypoxic …

In this paper, we discuss approaches our group has developed for the problem of imaging
the interior of dense scattering media [1]. While our principal focus is on potential biomedical …

The successful development and clinical use of instruments that perform real-time near-infra
red spectroscopy of transilluminated tissue has led to a widespread interest in the …

Frequency-domain studies of time-dependent light propagation in tissuelike phantoms that
contain optical heterogeneities are described. Specifically the phase shift and amplitude …

Near-infrared spectroscopy (NIRS) is an emerging technique for continuous, noninvasive
bedside monitoring of tissue structure, oxygenation, and blood flow. It relies upon the …

This paper describes an iterative perturbation approach for imaging the absorption
properties of a dense scattering medium. This method iteratively adjusts a current estimate …

A method for the reconstruction of 3-D images of the interior of dense scattering media,
based on the analysis of time-resolved backscattered signals is described. The method …

A principal difficulty encountered in dealing with highly diffused signals is that the inverse
problem is ill-posed and often underdetermined. A progressive expansion (PE) algorithm …

A physical model of how optical heterogeneities affect time-dependent measurements of
photon migration in tissue-like scattering media is presented. Using this model, changes in …

Near-infrared spectroscopy (NIRS) and near-infrared optical imaging (NIRI) are two medical
techniques under development, respectively offering the ability to use light to noninvasively …