Proteomics is a research field aiming to characterize molecular and cellular dynamics in
protein expression and function on a global level. The introduction of proteomics has been …

Proteomics provides powerful tools for the study of clinically relevant samples in the context
of translational cancer research. Here we briefly review applications of gel-based …

Non–small-cell lung cancers (NSCLC) compose 80% of all lung carcinomas with squamous
cell carcinomas (SCC) and adenocarcinoma representing the majority of these tumors …

Morphologic assessment of lung tumors is informative but insufficient to adequately predict
patient outcome. We previously identified transcriptional profiles that predict patient survival …

MicroRNAs (miRNAs), small noncoding RNAs that regulate target gene mRNAs, are known
to contribute to pathogenesis of cancers. Acute myeloid leukemia (AML) is a group of …

A direct, rapid, highly sensitive and specific biosensor for detection of cancer biomarkers is
desirable in early diagnosis and prognosis of cancer. However, the existing methods of …

Lung cancer is the leading cause of cancer death in men and women in Western nations,
and is among the deadliest cancers with a 5‐year survival rate of 15%. The high mortality …

Recent interest in cancer research focuses on predicting patients' survival by investigating
gene expression profiles based on microarray analysis. We propose a doubly penalized …

We examined the expression of oncoprotein 18 (Op18) in 93 lung adenocarcinomas and 10
uninvolved lung samples using quantitative two-dimensional PAGE analysis with …

The C-CRK gene, cellular homolog of the avian v-crk oncogene, encodes two alternatively
spliced adaptor signaling proteins, CRKI (28 kDa) and CRKII (40 kDa). Both CRKI and CRKII …