Deciphering breast cancer: from biology to the clinic

E Nolan, GJ Lindeman, JE Visvader - Cell, 2023 - cell.com
Breast cancer remains a leading cause of cancer-related mortality in women, reflecting
profound disease heterogeneity, metastasis, and therapeutic resistance. Over the last …

[HTML][HTML] SERS tags for biomedical detection and bioimaging

H Liu, X Gao, C Xu, D Liu - Theranostics, 2022 - ncbi.nlm.nih.gov
Surface-enhanced Raman scattering (SERS) has emerged as a valuable technique for
molecular identification. Due to the characteristics of high sensitivity, excellent signal …

[HTML][HTML] ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group

J Pascual, G Attard, FC Bidard, G Curigliano… - Annals of …, 2022 - Elsevier
Circulating tumour DNA (ctDNA) assays conducted on plasma are rapidly developing a
strong evidence base for use in patients with cancer. The European Society for Medical …

The potential of liquid biopsy in the management of cancer patients

A Markou, E Tzanikou, E Lianidou - Seminars in cancer biology, 2022 - Elsevier
Over the last decade, liquid biopsy has gained much attention as a powerful tool in
personalized medicine, since it enables monitoring cancer evolution and follow-up of cancer …

Addressing the benefits of inhibiting APOBEC3-dependent mutagenesis in cancer

M Petljak, AM Green, J Maciejowski, MD Weitzman - Nature genetics, 2022 - nature.com
Mutational signatures associated with apolipoprotein B mRNA-editing enzyme catalytic
polypeptide-like (APOBEC) 3 cytosine deaminase activity have been found in over half of …

Standard-of-care systemic therapy with or without stereotactic body radiotherapy in patients with oligoprogressive breast cancer or non-small-cell lung cancer …

CJ Tsai, JT Yang, N Shaverdian, J Patel, AF Shepherd… - The Lancet, 2024 - thelancet.com
Background Most patients with metastatic cancer eventually develop resistance to systemic
therapy, with some having limited disease progression (ie, oligoprogression). We aimed to …

Blood-based liquid biopsies for prostate cancer: clinical opportunities and challenges

B Trujillo, A Wu, D Wetterskog, G Attard - British journal of cancer, 2022 - nature.com
Liquid biopsy has been established as a powerful, minimally invasive, tool to detect clinically
actionable aberrations across numerous cancer types in real-time. With the development of …

Role of ctDNA in breast cancer

M Sant, A Bernat-Peguera, E Felip, M Margelí - Cancers, 2022 - mdpi.com
Simple Summary Circulating tumor DNA is DNA released by the tumor into the bloodstream.
In breast cancer, it is used mainly in research or in clinical trials, but it will likely be used in …

Emerging digital PCR technology in precision medicine

L Zhang, R Parvin, Q Fan, F Ye - Biosensors and Bioelectronics, 2022 - Elsevier
Digital PCR (dPCR) is built on partitioning reagent to the extent that single template
molecules are amplified and visualized individually, whereby offers higher precision and …

Breast cancer stem-like cells in drug resistance: a review of mechanisms and novel therapeutic strategies to overcome drug resistance

T Saha, KE Lukong - Frontiers in oncology, 2022 - frontiersin.org
Breast cancer is the most frequent type of malignancy in women worldwide, and drug
resistance to the available systemic therapies remains a major challenge. At the molecular …