The pathogenesis of periodontitis involves a complex immune/inflammatory cascade that is
initiated by the bacteria of the oral biofilm that forms naturally on the teeth. The susceptibility …

There has been little exploration of major biologic regulators of cerebral development in
autism. In archived neonatal blood of children with autistic spectrum disorders (n= 69) …

Dental pulp is a soft mesenchymal tissue densely innervated by afferent (sensory) fibers,
sympathetic fibers, and parasympathetic fibers. This complexity in pulp innervation has …

It is generally accepted that the nervous system contributes to the pathophysiology of
peripheral inflammation, and a neurogenic component has been implicated in many …

The human airways are innervated via efferent and afferent autonomic nerves, which
regulate many aspects of airway function. It has been suggested that neural control of the …

Neuropeptides represent an important category of endogenous contributors to the
establishment and maintenance of immune deviation in the immune‐privileged organs such …

The neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-
activating polypeptide (PACAP) down-regulate cytokine production. Because human septic …

Vasoactive intestinal peptide (VIP), a neuropeptide present in the lymphoid
microenvironment, and the structurally related pituitary adenylate cyclase-activating …

The pathogenesis of psoriasis is incompletely understood but cutaneous neurogenic
inflammation is probably involved. This involvement is suggested by a number of clinical …

Human airway smooth muscle cells (HASMC) secrete fractalkine (FKN), a chemokine the
concentration of which is increased in asthmatic patients. HASMC also induce mast cell …