The evolutional development of the RNA translation process that leads to protein synthesis based on naturally occurring amino acids has its continuation via synthetic biology, the so …
While grounded in the hard sciences of physics, chemistry, geology, and astronomy, as well as well-accepted principles in the life sciences, astrobiology remains the most speculative of …
SY Dai, D Yang - Journal of the American Chemical Society, 2020 - ACS Publications
Chemical modification of proteins in living cells permits valuable glimpses into the molecular interactions that underpin dynamic cellular events. While genetic engineering methods are …
M Wnętrzak, P Błażej, D Mackiewicz… - BMC Evolutionary …, 2018 - Springer
Background The standard genetic code (SGC) is a unique set of rules which assign amino acids to codons. Similar amino acids tend to have similar codons indicating that the code …
S Kim, H Yi, YT Kim, HS Lee - Journal of Molecular Biology, 2022 - Elsevier
The expansion of the genetic code consisting of four bases and 20 amino acids into diverse building blocks has been an exciting topic in synthetic biology. Many biochemical …
JL Schloßhauer, A Zemella, SK Dondapati… - Scientific Reports, 2023 - nature.com
Modification of proteins with a broad range of chemical functionalities enables the investigation of protein structure and activity by manipulating polypeptides at single amino …
JL Schloßhauer, N Cavak, A Zemella… - Frontiers in Molecular …, 2022 - frontiersin.org
The investigation of protein structures, functions and interactions often requires modifications to adapt protein properties to the specific application. Among many possible …
The main goal of synthetic biology (SB) is the creation of biodiversity applicable for biotechnological needs, while xenobiology (XB) aims to expand the framework of natural …
CJ Howard, BM Floyd, AM Bardo… - ACS chemical …, 2020 - ACS Publications
The field of proteomics has expanded recently with more sensitive techniques for the bulk measurement of peptides as well as single-molecule techniques. One limiting factor for …