Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

The high clinical mortality and economic burden posed by invasive fungal infections (IFIs),
along with significant agricultural crop loss caused by various fungal species, has resulted in …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

An estimated 58 million people have survived tuberculosis since 2000, yet many of them will
suffer from post-tuberculosis lung disease (PTLD). PTLD results from a complex interplay …

Abstract The European Society for Clinical Microbiology and Infectious Diseases, the
European Confederation of Medical Mycology and the European Respiratory Society Joint …

Invasive aspergillosis (IA) in haematology/oncology patients presents as primary infection or
breakthrough infection, which can become refractory to antifungal treatment and has a high …

Introduction Because of the high mortality of invasive fungal infections (IFIs), appropriate
exposure to antifungals appears to be crucial for therapeutic efficacy and safety. Materials …

Aspergillus fungi are the cause of an array of diseases affecting humans, animals and
plants. The triazole antifungal agents itraconazole, voriconazole, isavuconazole and …

Burn is an under-appreciated trauma that is associated with unacceptably high morbidity
and mortality. Although the survival rate after devastating burn injuries has continued to …

TB affects around 10.6 million people each year and there are now around 155 million TB
survivors. TB and its treatments can lead to permanently impaired health and wellbeing. In …