Application of chitosan with different molecular weights in cartilage tissue engineering

R Zhang, SJ Chang, Y Jing, LY Wang, CJ Chen… - Carbohydrate …, 2023 - Elsevier
Cartilage tissue engineering involves the invention of novel implantable cartilage
replacement materials to help heal cartilage injuries that do not heal themselves, aiming to …

Platelet-rich plasma therapy in the treatment of diseases associated with orthopedic injuries

J Fang, X Wang, W Jiang, Y Zhu, Y Hu… - … Engineering Part B …, 2020 - liebertpub.com
Platelet-rich plasma (PRP) is an autologous platelet concentrate prepared from the whole
blood that is activated to release growth factors (GFs) and cytokines and has been shown to …

Using platelet-rich plasma hydrogel to deliver mesenchymal stem cells into three-dimensional PLGA scaffold for cartilage tissue engineering

Y Tang, H Wang, Y Sun, Y Jiang, S Fang… - ACS Applied Bio …, 2021 - ACS Publications
The synthetic biodegradable polyester-based rigid porous scaffolds and cell-laden
hydrogels have been separately employed as therapeutic modality for cartilage repair …

[HTML][HTML] Repair of osteochondral defect using icariin-conditioned serum combined with chitosan in rabbit knees

J Zhang, D Ming, Q Ji, A Liu, C Zhang, J Jiao… - … medicine and therapies, 2020 - Springer
Background Osteochondral defects caused by an acute traumatic injury or articular
degeneration remains difficult to be manipulated. Repair of articular defects is still a great …

[HTML][HTML] Recent Achievements in the Development of Biomaterials Improved with Platelet Concentrates for Soft and Hard Tissue Engineering Applications

A Grzelak, A Hnydka, J Higuchi, A Michalak… - International Journal of …, 2024 - mdpi.com
Platelet concentrates such as platelet-rich plasma, platelet-rich fibrin or concentrated growth
factors are cost-effective autologous preparations containing various growth factors …

[HTML][HTML] Injectable Lyophilized Chitosan-Thrombin-Platelet-Rich Plasma (CS-FIIa-PRP) Implant to Promote Tissue Regeneration: In Vitro and Ex Vivo Solidification …

F Milano, A Chevrier, G De Crescenzo, M Lavertu - Polymers, 2023 - mdpi.com
Freeze-dried chitosan formulations solubilized in platelet-rich plasma (PRP) are currently
evaluated as injectable implants with the potential for augmenting the standard of care for …

[HTML][HTML] UDP-glucose dehydrogenase (UGDH) activity is suppressed by peroxide and promoted by PDGF in fibroblast-like synoviocytes: Evidence of a redox control …

R Chandrasekaran, C Mathieu, R Sheth, AP Cheng… - Plos one, 2022 - journals.plos.org
UDP-glucose dehydrogenase (UGDH) generates essential precursors of hyaluronic acid
(HA) synthesis, however mechanisms regulating its activity are unclear. We used enzyme …

Chitosan–platelet interactions

CD Hoemann, GE Rivard - Chitosan for Biomaterials III: Structure-Property …, 2021 - Springer
Since chitosan was identified as a hemostatic agent in the 1980s,“chitosan and platelets”
has developed into a topic of intense interest. This chapter gives an overview of platelet …

Effect of systemic administration of granulocyte colony-stimulating factor on a chronic partial-thickness cartilage defect in a rabbit knee joint

Y Ono, R Akagi, Y Mikami, M Shinohara… - Cartilage, 2021 - journals.sagepub.com
Objective Cartilage lesions in the knee joint can lead to joint mechanics changes and cause
knee pain. Bone marrow stimulation (BMS) promotes cartilage regeneration by perforating …

[HTML][HTML] The future of injectable orthobiologic substances for knee osteoarthritis: Options beyond platelet-rich plasma

S Patel, K Jindal, MS Dhillon - Journal of Musculoskeletal Surgery …, 2020 - journalmsr.com
The management of young arthritic knee and early grades of osteoarthritis (OA) aims to
reduce morbidity and improve the quality of life for which newer modalities are emerging …