[HTML][HTML] The safety and anti-ageing effects of nicotinamide mononucleotide in human clinical trials: an update

Q Song, X Zhou, K Xu, S Liu, X Zhu, J Yang - Advances in nutrition, 2023 - Elsevier
The importance of nicotinamide adenine dinucleotide (NAD+) in human physiology is well
recognized. As the NAD+ concentration in human skin, blood, liver, muscle and brain are …

A Review of Fibraurea tinctoria and Its Component, Berberine, as an Antidiabetic and Antioxidant

I Purwaningsih, IP Maksum, D Sumiarsa, S Sriwidodo - Molecules, 2023 - mdpi.com
Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia caused
by resistance to insulin action, inadequate insulin secretion, or excessive glucagon …

Oxidative stress, reductive stress and antioxidants in vascular pathogenesis and aging

M Mladenov, L Lubomirov, O Grisk, D Avtanski… - Antioxidants, 2023 - mdpi.com
This review is focused on the mechanisms that regulate health, disease and aging redox
status, the signal pathways that counteract oxidative and reductive stress, the role of food …

GDF‐15 Is Associated with Poor Physical Function in Prefrail Older Adults with Diabetes

RA Merchant, YH Chan, G Duque - Journal of Diabetes …, 2023 - Wiley Online Library
Introduction. Growth differentiation factor 15 (GDF‐15) has been shown to be a metabolic
and appetite regulator in diabetes mellitus (DM) and obesity. We aimed to investigate (i) the …

A pathophysiological intersection of diabetes and Alzheimer's disease

M Čater, SM Hölter - International journal of molecular sciences, 2022 - mdpi.com
Diabetes is among the most prevalent diseases of the modern world and is strongly linked to
an increased risk of numerous neurodegenerative disorders, although the exact …

Protective role of arachidonic acid against diabetic myocardial ischemic injury: a translational study of pigs, rats, and humans

Y Lv, K Li, S Wang, X Wang, G Yue, Y Zhang… - Cardiovascular …, 2024 - Springer
Aim Patients with diabetes mellitus have poor prognosis after myocardial ischemic injury.
However, the mechanism is unclear and there are no related therapies. We aimed to identify …

Serum-Stable Gold (III) Bisphosphine Complex Induces Mild Mitochondrial Uncoupling and In Vivo Antitumor Potency in Triple Negative Breast Cancer

AS Arojojoye, C Olelewe, S Gukathasan… - Journal of Medicinal …, 2023 - ACS Publications
The preparation of cyclometalated complexes offers a path to stable materials, catalysts, and
therapeutic agents. Here, we explore the anticancer potential of novel biphenyl organogold …

Comprehensive analysis of circRNA expression profiles in human brown adipose tissue

X Sun, X Wan, MA Khan, K Zhang, X Yi… - Diabetes, Metabolic …, 2023 - Taylor & Francis
Purpose Brown adipose tissue (BAT) can rapidly generate heat and improve energy
metabolism. Circular RNAs (circRNAs) are cellular endogenous non-coding RNAs, which …

Developmental stage-dependent changes in mitochondrial function in the brain of offspring following prenatal maternal immune activation

M Cieślik, A Zawadzka, GA Czapski… - International Journal of …, 2023 - mdpi.com
Maternal immune activation (MIA) is an important risk factor for neurodevelopmental
disorders such as autism. The aim of the current study was to investigate the development …

Ethyl-acetate fraction from a cinnamon-cortex extract protects pancreatic β-cells from oxidative stress damage

W Li, J Qiao, K Lin, P Sun, Y Wang, Q Peng… - Frontiers in …, 2023 - frontiersin.org
Background: The pathogenesis of diabetes mellitus is mediated mainly by oxidative stress
produced by damaged pancreatic β-cells. We identified that an ethyl-acetate fraction (EA) …