Despite centuries since the discovery and study of cancer, cancer is still a lethal and
intractable health issue worldwide. Cancer-associated fibroblasts (CAFs) have gained much …

Endothelial cells (ECs) constitute the innermost layer in all blood vessels to maintain the
structural integrity and microcirculation function for coronary microvasculature. Impaired …

In the present study, we used lipopolysaccharide‐(LPS‐) stimulated H9C2 cardiomyocytes
to investigate whether irisin treatment attenuates septic cardiomyopathy via Fundc1‐related …

Ethnopharmacological relevance Cerebral infarction is one of the most common types of
cerebrovascular diseases that threaten people's health. Compound Tongluo Decoction …

Pancreatic cancer (PC) is one of the most lethal malignancies, which is generally resistant to
various treatments. Tumor angiogenesis is deemed to be a pivotal rate-determining step for …

Head and neck squamous cell carcinoma (HNSCC) is the sixth leading malignancy
worldwide, with a poor prognosis and limited treatment options. Molecularly targeted …

In 1971, Folkman proposed that tumors could be limited to very small sizes by blocking
angiogenesis. Angiogenesis is the generation of new blood vessels from pre-existing …

Notch and Hedgehog signaling are involved in cancer biology and pathology, including the
maintenance of tumor cell proliferation, cancer stem-like cells, and the tumor …

Background: Invasive ductal carcinoma (IDC) is the most common type of metastatic breast
cancer. Due to the lack of valuable molecular biomarkers, the diagnosis and prognosis of …

Pancreatic cancer (PC) is a common malignant tumour in the digestive system. Due to the
lack of sensitive diagnostic markers, strong metastasis ability, and resistance to anti-cancer …