[HTML][HTML] PLGA-based composites for various biomedical applications

CV Rocha, V Gonçalves, MC da Silva… - International Journal of …, 2022 - mdpi.com
Polymeric materials have been extensively explored in the field of nanomedicine; within
them, poly lactic-co-glycolic acid (PLGA) holds a prominent position in micro-and …

PLGA-based nanoparticles as cancer drug delivery systems

FS Tabatabaei Mirakabad, K Nejati-Koshki… - Asian Pacific Journal …, 2014 - koreascience.kr
Poly (lactic-co-glycolic acid)(PLGA) is one of the most effective biodegradable polymeric
nanoparticles (NPs). It has been approved by the US FDA to use in drug delivery systems …

PLGA-based nanoparticles: A new paradigm in biomedical applications

S Sharma, A Parmar, S Kori, R Sandhir - TrAC trends in analytical chemistry, 2016 - Elsevier
Polymers were first introduced three decades ago as bioresorbable surgical devices. Since
then, polymer-based nanoparticles have been extensively studied in a variety of fields …

Theranostic polymeric nanoparticles for NIR imaging and photodynamic therapy

ET Sarcan, M Silindir-Gunay, AY Ozer - International journal of …, 2018 - Elsevier
Near-Infrared (NIR) dyes forming some of the photosensitizer agents show imaging and
therapy features by themselves. NIR dyes show photodynamic therapy by formation of …

Nanotechnology-based drug delivery to improve the therapeutic benefits of NRF2 modulators in cancer therapy

Z Sezgin-Bayindir, S Losada-Barreiro, C Bravo-Díaz… - Antioxidants, 2021 - mdpi.com
The disadvantages of conventional anticancer drugs, such as their low bioavailability, poor
targeting efficacy, and serious side effects, have led to the discovery of new therapeutic …

Encapsulation of quercetin-loaded β-lactoglobulin for drug delivery using modified anti-solvent method

Z Chavoshpour-Natanzi, M Sahihi - Food Hydrocolloids, 2019 - Elsevier
Many scientists use proteins as attractive bio-availability enhancers for natural compounds
and pharmaceuticals which have poor water solubility, due to their natural abundance …

The idiosyncratic efficacy of spironolactone-loaded PLGA nanoparticles against murine intestinal schistosomiasis

WE Abd El Hady, GA El-Emam, NE Saleh… - International Journal …, 2023 - Taylor & Francis
Background Schistosomiasis is a chronic debilitating parasitic disease accompanied with
severe mortality rates. Although praziquantel (PZQ) acts as the sole drug for the …

Association of nanoparticles and Nrf2 with various oxidative stress-mediated diseases

R Thiruvengadam, B Venkidasamy… - Chemico-Biological …, 2023 - Elsevier
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that regulates the
cellular antioxidant defense system at the posttranscriptional level. During oxidative stress …

Aloe vera and ofloxacin incorporated chitosan hydrogels show antibacterial activity, stimulate angiogenesis and accelerate wound healing in full thickness rat model

A Khan, A Andleeb, M Azam, S Tehseen… - … Research Part B …, 2023 - Wiley Online Library
Burns are potentially fatal and physically debilitating injuries, causing psychological and
physical scars and result in chronic disabilities. A well vascularized wound bed is required to …

Nanoparticulate systems for therapeutic and diagnostic applications

R Kammari, NG Das, SK Das - … for diagnostics, drug delivery and medical …, 2017 - Elsevier
Nanoparticle technology has been in the forefront of nanomedicine and innovative
healthcare devices. Although the concept is not new, the advances in biomaterials and the …