Fluorescence lifetime imaging microscopy (FLIM) has been rapidly developed over the past
30 years and widely applied in biomedical engineering. Recent progress in fluorophore …

Once an exotic add-on to fluorescence microscopy for life science research, fluorescence
lifetime imaging (FLIm) has become a powerful and increasingly utilised technique owing to …

Multifactor and multistep processes were elucidated to participate in the progression of non‐
small‐cell lung cancer (NSCLC). Circular RNA 0031250 (circ‐PRMT5) was a vital factor in …

While chemotherapy is an important and widely used therapeutic for cancer, it may facilitate
cancer metastasis. Herein, we report that human lung cancer cells exert higher invasion and …

Background It has been revealed that circular RNAs (circRNAs) play an important role in
regulating the malignant phenotype of tumor cells, thus involving in the progression of …

Lung cancer remains one of the most common malignant cancers worldwide, and its survival
rate is extremely low. Chemotherapy, the mainstay of lung cancer treatment, is not as …

Background Previous reports stated that DNA polymerase ζ is highly expressed in lung
cancer tissues. The present study aimed to investigate the roles and underlying mechanism …

Platinum anti-tumor drugs are currently the most widely used first-line chemotherapeutic
drugs in clinical practice, and their curative effects are remarkable. However, the problems of …

Genome duplication involves the orchestration of multiple DNA polymerases to ensure
faithful and complete DNA replication. Exogenous and endogenous factors can slow or stall …

Genome integrity is continually challenged by threats including DNA replication errors, toxic
metabolic byproducts, and exposure to exogenous genotoxins. Responding to and repairing …