Fine-needle aspiration diagnoses of noninvasive follicular variant of papillary thyroid carcinoma

BE Howitt, S Chang, M Eszlinger… - American journal of …, 2015 - academic.oup.com
Objectives Endocrine pathologists are reconsidering whether tumors characterized as
noninvasive follicular variant of papillary thyroid carcinoma (NFVPTC) warrant a diagnosis of …

Ruling in or ruling out thyroid malignancy by molecular diagnostics of thyroid nodules

M Eszlinger, L Hegedüs, R Paschke - Best practice & research Clinical …, 2014 - Elsevier
Routine morphologic cytology is the basis for any kind of (integrated) molecular FNA
diagnostics. The rule out (gene expression classifier) approach requires confirmation by …

Impact of molecular screening for point mutations and rearrangements in routine air-dried fine-needle aspiration samples of thyroid nodules

M Eszlinger, A Krogdahl, S Münz, C Rehfeld… - Thyroid, 2014 - liebertpub.com
Background: The diagnostic limitations of thyroid fine-needle aspiration (FNA), such as the
indeterminate category, can be partially overcome by molecular analyses. However, until …

Molecular analysis of residual ThinPrep material from thyroid FNAs increases diagnostic sensitivity

JF Krane, ES Cibas, EK Alexander… - Cancer …, 2015 - Wiley Online Library
BACKGROUND Molecular testing for genetic alterations associated with malignancy is a
potential triage approach for thyroid fine‐needle aspiration (FNA) samples with …

Molecular testing of thyroid fine-needle aspirations improves presurgical diagnosis and supports the histologic identification of minimally invasive follicular thyroid …

M Eszlinger, S Piana, A Moll, E Bösenberg, A Bisagni… - Thyroid, 2015 - liebertpub.com
Background: Previous studies detecting mutations in thyroid nodule fine-needle aspiration
(FNA) material differed with respect to the cytologic grading applied to the FNAs, the type of …

FNA smears as a potential source of DNA for targeted next‐generation sequencing of lung adenocarcinomas

AL Treece, ND Montgomery, NM Patel… - Cancer …, 2016 - Wiley Online Library
BACKGROUND Diff‐Quik–stained fine‐needle aspiration (FNA) smears and touch
preparations from biopsies represent alternative specimens for molecular testing when cell …

Evaluation of a two-year routine application of molecular testing of thyroid fine-needle aspirations using a seven-gene panel in a primary referral setting in Germany

M Eszlinger, K Böhme, M Ullmann, F Görke, U Siebolts… - Thyroid, 2017 - liebertpub.com
Background: Major differences with respect to the diagnostic performance of a “ruling in”
approach in the presurgical diagnosis of indeterminate thyroid fine-needle aspirations …

Young investigator challenge: can the Ion AmpliSeq Cancer Hotspot Panel v2 be used for next‐generation sequencing of thyroid FNA samples?

C Bellevicine, R Sgariglia, U Malapelle… - Cancer …, 2016 - Wiley Online Library
BACKGROUND Fine‐needle aspiration (FNA) cytology is accurate and cost‐effective in the
evaluation of thyroid nodules. Molecular techniques may contribute to risk stratification in …

Somatic mutations in 33 benign and malignant hot thyroid nodules in children and adolescents

M Eszlinger, M Niedziela, E Typlt, H Jaeschke… - Molecular and cellular …, 2014 - Elsevier
Hot thyroid nodules (HTNs) in children are rare. Their reported malignancy rate is higher
than in adults. However molecular data are rare. We present clinical and molecular data for …

Molecular diagnosis using residual liquid-based cytology materials for patients with nondiagnostic or indeterminate thyroid nodules

H Kwon, WG Kim, M Eszlinger… - Endocrinology and …, 2016 - synapse.koreamed.org
Background Molecular analysis for common somatic mutations in thyroid cancer can
improve diagnostic accuracy of fine-needle aspiration cytology (FNAC) in the nondiagnostic …