Safety and efficacy of daridorexant in patients with insomnia disorder: results from two multicentre, randomised, double-blind, placebo-controlled, phase 3 trials

E Mignot, D Mayleben, I Fietze, D Leger… - The Lancet …, 2022 - thelancet.com
Background Daytime functioning is impaired in people with insomnia disorder. Currently
available dual orexin receptor antagonists have shown efficacy in insomnia disorder, but do …

Sleep quality and COVID-19 outcomes: the evidence-based lessons in the framework of predictive, preventive and personalised (3P) medicine

K Richter, S Kellner, T Hillemacher, O Golubnitschaja - EPMA Journal, 2021 - Springer
Sleep quality and duration play a pivotal role in maintaining physical and mental health. In
turn, sleep shortage, deprivation and disorders are per evidence the risk factors and …

[HTML][HTML] A systematic review of potentially inappropriate medications use and related costs among the elderly

SK Malakouti, J Javan-Noughabi… - Value in health regional …, 2021 - Elsevier
Abstract Objective Potentially inappropriate medications (PIMs) use is a common
phenomenon among older adults. This paper aimed to perform a systematic literature review …

The association between health status and insomnia, mental health, and preventive behaviors: the mediating role of fear of COVID-19

DK Ahorsu, CY Lin, AH Pakpour - Gerontology and Geriatric …, 2020 - journals.sagepub.com
Objectives: This study examined the mediation role of fear of COVID-19 in the association
between perceived health status of older adults and their insomnia, mental health, and …

The differential impact of COVID-19 lockdown on sleep quality, insomnia, depression, stress, and anxiety among late adolescents and elderly in Italy

G Amicucci, F Salfi, A D'Atri, L Viselli, M Ferrara - Brain Sciences, 2021 - mdpi.com
The restraining measures due to the COVID-19 outbreak deeply affected the general
population's sleep health and psychological status. The current literature proposes young …

Prevalence of sleep-related problems and risks in a community-dwelling older adult population: a cross-sectional survey-based study

NP Gordon, JH Yao, LA Brickner, JC Lo - BMC Public Health, 2022 - Springer
Background Despite evidence of adverse health consequences of inadequate restorative
sleep for older adults, assessment of sleep quantity, quality, and use of sleep aids is not …

Prevalence and factors associated with insomnia among medical students in China during the COVID-19 pandemic: characterization and associated factors

M Zhang, L Qin, D Zhang, M Tao, K Han, C Chi… - BMC psychiatry, 2023 - Springer
Background Insomnia has become an important issue in recent years. Insomnia is affected
by many factors. Previous research has shown that during the COVID-19 pandemic, there …

Two years after lockdown: Longitudinal trajectories of sleep disturbances and mental health over the COVID‐19 pandemic, and the effects of age, gender and …

F Salfi, G Amicucci, D Corigliano… - Journal of Sleep …, 2023 - Wiley Online Library
Since the first lockdown of Spring 2020, the COVID‐19 contagion waves pervasively
disrupted the sleep and mental health of the worldwide population. Notwithstanding the …

The fall of vulnerability to sleep disturbances in evening chronotypes when working from home and its implications for depression

F Salfi, A D'Atri, G Amicucci, L Viselli, M Gorgoni… - Scientific Reports, 2022 - nature.com
Eveningness is distinctively associated with sleep disturbances and depression symptoms
due to the misalignment between biological and social clocks. The widespread imposition of …

Insomnia symptoms and incident heart failure: a population-based cohort study

A Mahmood, M Ray, A Dobalian, KD Ward… - European heart …, 2021 - academic.oup.com
Aims Heart failure (HF) is an ongoing epidemic and a serious clinical and public health
issue. Currently, little is known about prospective associations between insomnia symptoms …