The coagulation, fibrinolytic, anticoagulation, and complement systems are in delicate
balance with the vessel wall endothelium ensuring appropriate hemostasis. Coagulopathy …

Background Long-COVID is characterized by prolonged, diffuse symptoms months after
acute COVID-19. Accurate diagnosis and targeted therapies for Long-COVID are lacking …

Fibrinolysis is a series of enzymatic reactions that degrade insoluble fibrin. Plasminogen
activators convert the zymogen plasminogen to the active serine protease plasmin, which …

The infectious respiratory condition COVID-19 manifests a clinical course ranging from
mild/moderate up-to critical systemic dysfunction and death linked to thromboinflammation …

Objectives Extracellular histone levels are associated with the severity of many human
pathologies, including sepsis and COVID-19. This study aimed to investigate the role of …

Galectin-3 is a beta-galactoside-binding lectin involved in inflammation and lung fibrosis
and postulated to enhance thrombosis. In COVID-19, it is considered to be a prognostic …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection results in
coagulation activation although it is usually not associated with consumption coagulopathy …

Inflammation-induced coagulopathy is a common complication associated with coronavirus
disease 2019 (COVID-19). We aim to evaluate the association of NETosis and complement …

Critically ill patients infected with SARS-CoV-2 display adaptive immunity, but it is unknown
if they develop cross-reactivity to variants of concern (VOCs). We profiled cross-immunity …

Background Sepsis remains a major cause of mortality in intensive care units (ICUs). Prompt
diagnosis and effective management are imperative for better outcomes. In this systematic …