Neural versus alternative integrative systems: molecular insights into origins of neurotransmitters
LL Moroz, DY Romanova… - … Transactions of the …, 2021 - royalsocietypublishing.org
Transmitter signalling is the universal chemical language of any nervous system, but little is
known about its early evolution. Here, we summarize data about the distribution and …
known about its early evolution. Here, we summarize data about the distribution and …
Evolution of glutamatergic signaling and synapses
Glutamate (Glu) is the primary excitatory transmitter in the mammalian brain. But, we know
little about the evolutionary history of this adaptation, including the selection of l-glutamate …
little about the evolutionary history of this adaptation, including the selection of l-glutamate …
Amino acids integrate behaviors in nerveless placozoans
MA Nikitin, DY Romanova, SI Borman… - Frontiers in …, 2023 - frontiersin.org
Placozoans are the simplest known free-living animals without recognized neurons and
muscles but a complex behavioral repertoire. However, mechanisms and cellular bases of …
muscles but a complex behavioral repertoire. However, mechanisms and cellular bases of …
The diversification and lineage-specific expansion of nitric oxide signaling in Placozoa: insights in the evolution of gaseous transmission
Nitric oxide (NO) is a ubiquitous gaseous messenger, but we know little about its early
evolution. Here, we analyzed NO synthases (NOS) in four different species of placozoans …
evolution. Here, we analyzed NO synthases (NOS) in four different species of placozoans …
[HTML][HTML] Nonsynaptic encoding of behavior by neuropeptides
Highlights•Neuropeptide signaling forms a chemical connectome overlaid on synaptic
circuits.•Studies on nonbilaterians have revealed nonsynaptic actions of neuropeptides.• …
circuits.•Studies on nonbilaterians have revealed nonsynaptic actions of neuropeptides.• …
Selective advantages of synapses in evolution
LL Moroz, DY Romanova - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
The common ancestor of all Metazoa (Urmetazoan) was a nerveless animal (Mackie, 1970,
1990; Moroz, 2009). This hypothetical Urmetazoan likely used electrical and chemical …
1990; Moroz, 2009). This hypothetical Urmetazoan likely used electrical and chemical …
Sodium action potentials in placozoa: Insights into behavioral integration and evolution of nerveless animals
Placozoa are small disc-shaped animals, representing the simplest known, possibly
ancestral, organization of free-living animals. With only six morphological distinct cell types …
ancestral, organization of free-living animals. With only six morphological distinct cell types …
Hidden cell diversity in Placozoa: ultrastructural insights from Hoilungia hongkongensis
DY Romanova, FÚÚ Varoqueaux, J Daraspe… - Cell and tissue …, 2021 - Springer
From a morphological point of view, placozoans are among the most simple free-living
animals. This enigmatic phylum is critical for our understanding of the evolution of animals …
animals. This enigmatic phylum is critical for our understanding of the evolution of animals …
Glycine as a signaling molecule and chemoattractant in Trichoplax (Placozoa): insights into the early evolution of neurotransmitters
DY Romanova, A Heyland, D Sohn, AB Kohn… - …, 2020 - journals.lww.com
The origin and early evolution of neurotransmitter signaling in animals are unclear due to
limited comparative information, primarily about prebilaterian animals. Here, we performed …
limited comparative information, primarily about prebilaterian animals. Here, we performed …
The enigmatic Placozoa part 1: Exploring evolutionary controversies and poor ecological knowledge
B Schierwater, HJ Osigus, T Bergmann… - …, 2021 - Wiley Online Library
The placozoan Trichoplax adhaerens is a tiny hairy plate and more simply organized than
any other living metazoan. After its original description by FE Schulze in 1883, it attracted …
any other living metazoan. After its original description by FE Schulze in 1883, it attracted …